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| | 1H-Pyrrole-1-propanoic acid, 2,5-dihydro-2,5-dioxo-, 2,3,4,5,6-pentafluorophenyl ester Basic information |
| Product Name: | 1H-Pyrrole-1-propanoic acid, 2,5-dihydro-2,5-dioxo-, 2,3,4,5,6-pentafluorophenyl ester | | Synonyms: | 1H-Pyrrole-1-propanoic acid, 2,5-dihydro-2,5-dioxo-, 2,3,4,5,6-pentafluorophenyl ester;perfluorophenyl 3-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)propanoate;(2,3,4,5,6-Pentafluorophenyl) 3-(2,5-dioxopyrrol-1-yl)propanoate | | CAS: | 138194-55-5 | | MF: | C13H6F5NO4 | | MW: | 335.18 | | EINECS: | | | Product Categories: | | | Mol File: | 138194-55-5.mol |  |
| | 1H-Pyrrole-1-propanoic acid, 2,5-dihydro-2,5-dioxo-, 2,3,4,5,6-pentafluorophenyl ester Chemical Properties |
| Boiling point | 407.5±45.0 °C(Predicted) | | density | 1.621±0.06 g/cm3(Predicted) | | pka | -2.38±0.20(Predicted) |
| | 1H-Pyrrole-1-propanoic acid, 2,5-dihydro-2,5-dioxo-, 2,3,4,5,6-pentafluorophenyl ester Usage And Synthesis |
| Uses | Mal-PFP ester is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1]. | | IC 50 | Alkyl/ether | | References | [1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
| | 1H-Pyrrole-1-propanoic acid, 2,5-dihydro-2,5-dioxo-, 2,3,4,5,6-pentafluorophenyl ester Preparation Products And Raw materials |
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