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| | NH2-noda-ga Basic information |
| Product Name: | NH2-noda-ga | | Synonyms: | 1H-1,4,7-Triazonine-1,4,7-triacetic acid, α1-[3-[(2-aminoethyl)amino]-3-oxopropyl]hexahydro-;NH2-noda-ga | | CAS: | 1630114-57-6 | | MF: | C17H31N5O7 | | MW: | 417.46 | | EINECS: | | | Product Categories: | | | Mol File: | 1630114-57-6.mol |  |
| | NH2-noda-ga Chemical Properties |
| Boiling point | 767.8±60.0 °C(Predicted) | | density | 1.306±0.06 g/cm3(Predicted) | | pka | 1.55±0.10(Predicted) |
| | NH2-noda-ga Usage And Synthesis |
| Uses | NH2-NODAGA is a NODAGA-type metal chelator that can bind to radionuclides to prepare radionuclide conjugates (RDCs). NH2-NODAGA can react with diethyl squarate in 0.5M phosphate buffer (room temperature, 2 h, pH 7-7.5) to obtain NODAGA.SA. NODAGA.SA can target L-lysine urea-L-glutamate (KuE), which is a key structure of prostate-specific membrane antigen (PSMA). NODAGA.SA.KuE can bind [68]Ga and can be used for PET examination of NMRInu/nu nude mice bearing LNCaP tumors. | | IC 50 | RDC Bifunctional Chelator |
| | NH2-noda-ga Preparation Products And Raw materials |
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