5'-EthylcarboxaMido-2',3'-isopropylidene Adenosine

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5'-EthylcarboxaMido-2',3'-isopropylidene Adenosine Basic information
Product Name:5'-EthylcarboxaMido-2',3'-isopropylidene Adenosine
Synonyms:5'-ETHYLCARBOXAMIDO-2',3'-ISOPROPYLIDENEADENOSINE;1-(6-Amino-9H-purin-9-yl)-1-deoxy-N-ethyl-2,3-O-(1-methylethylidene)--D-ribofuranuronamide;2’,3’-O-isopropylidene-NECA;5'-Ethylcarboxamido-2',3'-O-isopropylideneadenosine;b-D-RibofuranuronaMide,1-(6-aMino-9H-purin-9-yl)-1-deoxy-N-ethyl-2,3-O-(1-Methylethylidene)-;β-D-Ribofuranuronamide, 1-(6-amino-9H-purin-9-yl)-1-deoxy-N-ethyl-2,3-O-(1-methylethylidene)-
CAS:39491-53-7
MF:C15H20N6O4
MW:348.36
EINECS:
Product Categories:Bases & Related Reagents;Carbohydrates & Derivatives;Heterocycles;Nucleotides
Mol File:39491-53-7.mol
5'-EthylcarboxaMido-2',3'-isopropylidene Adenosine Structure
5'-EthylcarboxaMido-2',3'-isopropylidene Adenosine Chemical Properties
Melting point 200-202°C
density 1.69±0.1 g/cm3(Predicted)
solubility DMSO, Ethanol, Methanol
form Solid
pka14.47±0.60(Predicted)
color Pale Yellow
Safety Information
MSDS Information
5'-EthylcarboxaMido-2',3'-isopropylidene Adenosine Usage And Synthesis
Chemical PropertiesPale Yellow Solid
UsesAs a useful template for the development of A2B adenosine receptor agonists, 5'-EthylcarboxaMido-2',3'-isopropylidene Adenosine was confirmed to be a full agonist in a functional assay based on the measurement of its capacity to modulate cAMP levels in CHO cells expressing the hA2B receptor.
UsesA useful template for the development of A2B adenosine receptor agonists. It was confirmed to be a full agonist in a functional assay based on the measurement of its capacity to modulate cAMP levels in CHO cells expressing the hA2B receptor.
5'-EthylcarboxaMido-2',3'-isopropylidene Adenosine Preparation Products And Raw materials
Raw materialsβ-D-Ribofuranuronoyl chloride, 1-(6-amino-9H-purin-9-yl)-1-deoxy-2,3-O-(1-methylethylidene)- (9CI)-->2',3'-Isopropylidene Adenosine-5'-carboxylic Acid-->Ethylamine
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