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Biolab Reagents |
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027-65279366 18108604356 |
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products@biolabreagent.com |
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ACROBiosystems |
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13121935750 |
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| | ANTI-FRIZZLED-10 Basic information |
| Product Name: | ANTI-FRIZZLED-10 | | Synonyms: | Anti-Frizzled-10 antibody produced in rabbit;Anti-FZD10 antibody produced in rabbit;CD350 antigen;ANTI-FZD10;ANTI-FRIZZLED-10;Anti-hFz10;Anti-CD350 antigen;Anti-Frizzled-10 precursor | | CAS: | | | MF: | | | MW: | 0 | | EINECS: | | | Product Categories: | | | Mol File: | Mol File | ![ANTI-FRIZZLED-10 Structure]() |
| | ANTI-FRIZZLED-10 Chemical Properties |
| storage temp. | −20°C | | form | buffered aqueous solution | | biological source | rabbit |
| WGK Germany | - | | Storage Class | 10 - Combustible liquids |
| | ANTI-FRIZZLED-10 Usage And Synthesis |
| Uses | Anti-Frizzled-10 antibody is suitable for immunohistochemistry study (formalin-fixed, paraffin-embedded sections) at a concentration of 3μg/mL using human kidney, cortex. | | Biochem/physiol Actions | Frizzled homolog protein (FZD) is a seven-pass transmembrane type receptor expressed in various normal tissues such as skeletal muscle, kidney, pancreas, cerebellum and cerebral cortex. In humans, ten members (FZD1-FZD10) of Frizzled homolog protein have been identified. FZD10, a cell-surface receptor molecules in the Wnt pathway, is expressed during development in embryonic limbs, neural tube, and central nervous system and mediates Wnt signaling. It was reported that FZD10 plays a critical role in the metastasis of synovial sarcoma. Mechanistically, it facilitates the activation of Dvl-Rac1-JNK axis of planar cell polarity (PCP) signaling, with no effect on nuclear β-catenin accumulation and Tcf/Lef reporter activity. |
| | ANTI-FRIZZLED-10 Preparation Products And Raw materials |
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