| Company Name: |
BOC Sciences |
| Tel: |
1-631-485-4226; 16314854226 |
| Email: |
info@bocsci.com |
Lys-006 manufacturers
- LYS006
-
- $893.00
-
2026-07-14
- CAS:1799681-85-8
- Purity: 99.33%
- Supply Ability: 10g
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| | Lys-006 Basic information |
| Product Name: | Lys-006 | | Synonyms: | 2H-Tetrazole-2-butanoic acid, β-amino-5-[4-[(5-chloro-3-fluoro-2-pyridinyl)oxy]phenyl]-, (βS)-;βS-amino-5-[4-[(5-chloro-3-fluoro-2-pyridinyl)oxy]phenyl]-2H-tetrazole-2-butanoic acid;(S)-3-Amino-4-(5-(4-((5-chloro-3-fluoropyridin-2-yl)oxy)phenyl)-2H-tetrazol-2-yl)butanoic acid;(3S)-3-amino-4-(5-{4-[(5-chloro-3-fluoropyridin-2-yl)oxy]phenyl}-2H-1,2,3,4-tetrazol-2-yl)butanoic acid;LYS006 hcl;LTA4H-IN-1;Lys-006 | | CAS: | 1799681-85-8 | | MF: | C16H14ClFN6O3 | | MW: | 392.78 | | EINECS: | | | Product Categories: | | | Mol File: | 1799681-85-8.mol |  |
| | Lys-006 Chemical Properties |
| Boiling point | 583.1±60.0 °C(Predicted) | | density | 1.60±0.1 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | DMSO : 250 mg/mL (636.50 mM; Need ultrasonic) | | form | A solid | | pka | 3.54±0.10(Predicted) | | color | White to off-white |
| | Lys-006 Usage And Synthesis |
| Uses | LTA4H-IN-1 is a potent inhibitor of leukotriene A4 hydrolase (LTA4H) extracted from patent WO2015092740A1, example 29, has an IC50 of 2 nM. LTA4H-IN-1 can be used for the research of inflammatory and autoimmune disorders[1]. | | in vivo | LTA4H-IN-1 (0.3 mg/kg; a single p.o.) inhibits the -43% release of LTB4 compared with vehicle control in mice[1]. | | IC 50 | LTA4H hydrolase: 2 nM (IC50) | | References | [1] Bollbuck B, et, al. Heteroaryl butanoic acid derivatives as leukotriene A4 hydrolase inhibitors and their preparation, pharmaceutical compositions and use in the treatment of diseases. WO2015092740A1. |
| | Lys-006 Preparation Products And Raw materials |
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