Quinoline, 7-fluoro-6-methoxy-4-[6-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]pyrazolo[1,5-a]pyrimidin-3-yl]-

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Quinoline, 7-fluoro-6-methoxy-4-[6-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]pyrazolo[1,5-a]pyrimidin-3-yl]- Basic information
Product Name:Quinoline, 7-fluoro-6-methoxy-4-[6-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]pyrazolo[1,5-a]pyrimidin-3-yl]-
Synonyms:Quinoline, 7-fluoro-6-methoxy-4-[6-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]pyrazolo[1,5-a]pyrimidin-3-yl]-;ALK2-IN-4
CAS:2248154-85-8
MF:C26H30FN7O
MW:475.56
EINECS:
Product Categories:
Mol File:2248154-85-8.mol
Quinoline, 7-fluoro-6-methoxy-4-[6-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]pyrazolo[1,5-a]pyrimidin-3-yl]- Structure
Quinoline, 7-fluoro-6-methoxy-4-[6-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]pyrazolo[1,5-a]pyrimidin-3-yl]- Chemical Properties
density 1.38±0.1 g/cm3(Predicted)
pka8.14±0.42(Predicted)
form Solid
color Light yellow to yellow
Safety Information
MSDS Information
Quinoline, 7-fluoro-6-methoxy-4-[6-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]pyrazolo[1,5-a]pyrimidin-3-yl]- Usage And Synthesis
UsesALK2-IN-4 is a potent ALK2 inhibitor extracted from patent WO2020086963A1, compound Formula I free base[1].
IC 50ACVR1
References[1] Sarah Bethune, et al. Crystal forms of an alk2 inhibitor. WO2020086963A1.
Quinoline, 7-fluoro-6-methoxy-4-[6-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]pyrazolo[1,5-a]pyrimidin-3-yl]- Preparation Products And Raw materials
Tag:Quinoline, 7-fluoro-6-methoxy-4-[6-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]pyrazolo[1,5-a]pyrimidin-3-yl]-(2248154-85-8) Related Product Information
Quinoline, 7-fluoro-6-methoxy-4-[6-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]pyrazolo[1,5-a]pyrimidin-3-yl]- ALK2-IN-4 succinate Activin RIB/ALK-4 Protein, Human (HEK293, Fc) BMPR1A/ALK-3 Protein, Canine (HEK293, Fc) TGFBR1/ALK-5 Protein, Human (HEK293, mFc-Avi) TGFBR2/TGF-beta RII protein, Human (Biotinylated, HEK293, Fc-Avi)