4H-Cyclopenta[b]thiophene-3-carboxamide, 2-[[2-[(5-cyclopropyl-4-phenyl-4H-1,2,4-triazol-3-yl)thio]-1-oxopropyl]amino]-5,6-dihydro-

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4H-Cyclopenta[b]thiophene-3-carboxamide, 2-[[2-[(5-cyclopropyl-4-phenyl-4H-1,2,4-triazol-3-yl)thio]-1-oxopropyl]amino]-5,6-dihydro- Suppliers list
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4H-Cyclopenta[b]thiophene-3-carboxamide, 2-[[2-[(5-cyclopropyl-4-phenyl-4H-1,2,4-triazol-3-yl)thio]-1-oxopropyl]amino]-5,6-dihydro- manufacturers

  • MASM7
  • MASM7 pictures
  • $66.00
  • 2026-06-02
  • CAS:920868-45-7
  • Purity: 99.56%
  • Supply Ability: 10g
4H-Cyclopenta[b]thiophene-3-carboxamide, 2-[[2-[(5-cyclopropyl-4-phenyl-4H-1,2,4-triazol-3-yl)thio]-1-oxopropyl]amino]-5,6-dihydro- Basic information
Product Name:4H-Cyclopenta[b]thiophene-3-carboxamide, 2-[[2-[(5-cyclopropyl-4-phenyl-4H-1,2,4-triazol-3-yl)thio]-1-oxopropyl]amino]-5,6-dihydro-
Synonyms:4H-Cyclopenta[b]thiophene-3-carboxamide, 2-[[2-[(5-cyclopropyl-4-phenyl-4H-1,2,4-triazol-3-yl)thio]-1-oxopropyl]amino]-5,6-dihydro-;2-{2-[(5-cyclopropyl-4-phenyl-4H-1,2,4-triazol-3-yl)sulfanyl]propanamido}-4H,5H,6H-cyclopenta[b]thiophene-3-carboxamide;MASM-7,2 {2 [(5 cyclopropyl 4 phenyl 4H 1,2,4 triazol 3 yl)sulfanyl]propanamido} 4H,5H,6H cyclopenta[b]thiophene 3 carboxamide,Inhibitor,mitofusins,MASM7,mitochondrial,MASM 7,molecule activator,inhibit,MEFs,2{2[(5cyclopropyl4phenyl4H1,2,4triazol3yl)sulfanyl]propanamido}4H,5H,6Hcyclopenta[b]thiophene3carboxamide;MASM7;2-(2-((5-cyclopropyl-4-phenyl-4H-1,2,4-triazol-3-yl)thio)propanamido)-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxamide;MASM7, 10 mM in DMSO;2-(2-((5-Cyclopropyl-4-phenyl-4H-[1,2,4]-triazol-3-yl)thio)-propancarboxcarboxcarboxamido)-5,6-dihydro-4H-cyclopenta[b]thiophen-3-carboxamide
CAS:920868-45-7
MF:C22H23N5O2S2
MW:453.58
EINECS:
Product Categories:
Mol File:920868-45-7.mol
4H-Cyclopenta[b]thiophene-3-carboxamide, 2-[[2-[(5-cyclopropyl-4-phenyl-4H-1,2,4-triazol-3-yl)thio]-1-oxopropyl]amino]-5,6-dihydro- Structure
4H-Cyclopenta[b]thiophene-3-carboxamide, 2-[[2-[(5-cyclopropyl-4-phenyl-4H-1,2,4-triazol-3-yl)thio]-1-oxopropyl]amino]-5,6-dihydro- Chemical Properties
density 1.57±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
pka12.45±0.20(Predicted)
form Solid
color Off-white to yellow
Safety Information
MSDS Information
4H-Cyclopenta[b]thiophene-3-carboxamide, 2-[[2-[(5-cyclopropyl-4-phenyl-4H-1,2,4-triazol-3-yl)thio]-1-oxopropyl]amino]-5,6-dihydro- Usage And Synthesis
UsesMASM7 is a mitofusin activator, and can achieve mitochondrial fusion via mitofusins. MASM7 can increase Mito AR with an EC50 value of 75 nM in MEFs in concentration-responsively, and can promote mitochondrial fusion by directly activating MFN2 or MFN. MASM7 also demonstrates direct binding to the HR2 domain of MFN2 with Kd value of 1.1 μM[1].
References[1] Emmanouil Zacharioudakis, et al. Modulating mitofusins to control mitochondrial function and signaling. Nat Commun. 2022 Jul 7;13(1):3775. DOI:10.1038/s41467-022-31324-1
4H-Cyclopenta[b]thiophene-3-carboxamide, 2-[[2-[(5-cyclopropyl-4-phenyl-4H-1,2,4-triazol-3-yl)thio]-1-oxopropyl]amino]-5,6-dihydro- Preparation Products And Raw materials
Tag:4H-Cyclopenta[b]thiophene-3-carboxamide, 2-[[2-[(5-cyclopropyl-4-phenyl-4H-1,2,4-triazol-3-yl)thio]-1-oxopropyl]amino]-5,6-dihydro-(920868-45-7) Related Product Information
2-[(5-benzyl-4-phenyl-4H-1,2,4-triazol-3-yl)sulfanyl]-N-(3-cyano-4,5,6,7-tetrahydro-1-benzothien-2-yl)acetamide N-(3-cyano-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)-2-[[5-[(4-methylanilino)methyl]-4-phenyl-1,2,4-triazol-3-yl]sulfanyl]acetamide 4H-Cyclopenta[b]thiophene-3-carboxamide, 2-[[2-[(5-cyclopropyl-4-phenyl-4H-1,2,4-triazol-3-yl)thio]-1-oxopropyl]amino]-5,6-dihydro- N-(3-cyano-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)-2-[[5-[(3-methylanilino)methyl]-4-phenyl-1,2,4-triazol-3-yl]sulfanyl]acetamide FCCP Carbonyl cyanide 3-chlorophenylhydrazone