| Company Name: |
BOC Sciences |
| Tel: |
16314854226; +8616314854226 |
| Email: |
inquiry@bocsci.com |
|
| | L-glutamic acid, compound with erythromycin (1:1) Basic information |
| | L-glutamic acid, compound with erythromycin (1:1) Chemical Properties |
| | L-glutamic acid, compound with erythromycin (1:1) Usage And Synthesis |
| Description | Erythromycin glutamate is a macrolide bacteriostatic antibiotic often used in Serbia, especially in the treatment of respiratory infections. This antibiotic is metabolized through the liver and inhibits cytochrome enzyme P450A (CYP) 3A41. _x000D_
. | | Uses | Erythromycin glutamate is a macrolide antibiotic produced by actinomycete Streptomyces erythreus with a broad spectrum of antimicrobial activity. Erythromycin glutamate binds to bacterial 50S ribosomal subunits and inhibits RNA-dependent protein synthesis by blockage of transpeptidation and/or translocation reactions, without affecting synthesis of nucleic acid[1][2]. Erythromycin glutamate also exhibits antitumor and neuroprotective effect in different fields of research[3][4]. | | References | [1] Gribble MJ, et al. Erythromycin. Med Clin North Am. 1982 Jan;66(1):79-89. DOI:10.1016/s0025-7125(16)31443-2
[2] Nakornchai S, et al. Activity of azithromycin or erythromycin in combination with antimalarial drugs against multidrug-resistant Plasmodium falciparum in vitro. Acta Trop. 2006 Dec;100(3):185-91. Epub 2006 Nov 28. DOI:10.1016/j.actatropica.2006.10.008
[3] Hamada K, et al. Antitumor effect of erythromycin in mice. Chemotherapy. 1995 Jan-Feb. 41(1):59-69. DOI:10.1159/000239325
[4] Katayama Y, et al. Neuroprotective effects of erythromycin on cerebral ischemia reperfusion-injury and cell viability after oxygen-glucose deprivation in cultured neuronal cells. Brain Res. 2014 Nov 7. 1588:159-67. DOI:10.1016/j.brainres.2014.09.016 |
| | L-glutamic acid, compound with erythromycin (1:1) Preparation Products And Raw materials |
|