Kisspeptin-234 trifluoroacetate

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Company Name: Hangzhou Peptidego Biotech Co.,Ltd.  
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Company Name: TargetMol Chemicals Inc.  
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Company Name: Hangzhou Sinoda Pharmaceutical Technology Co. LTD  
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Company Name: Shanghai Yifei Biotechnology Co. , Ltd.  
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Kisspeptin-234 trifluoroacetate Basic information
Product Name:Kisspeptin-234 trifluoroacetate
Synonyms:Kisspeptin 234(TFA）;Kisspeptin-234 trifluoroacetate
CAS:1848962-29-7
MF:C65H79F3N18O15
MW:1409.45
EINECS:
Product Categories:
Mol File:1848962-29-7.mol
Kisspeptin-234 trifluoroacetate Structure
Kisspeptin-234 trifluoroacetate Chemical Properties
solubility DMF: Slightly Soluble
DMSO: Slightly Soluble
form Solid
color White to off-white
SequenceAc-Ala-Asn-Trp-Asn-Gly-Phe-Gly-Trp-Arg-Phe-NH2
Safety Information
MSDS Information
Kisspeptin-234 trifluoroacetate Usage And Synthesis
UsesKisspeptin 234 TFA, is a 10 amino acid peptide as well as a kisspeptin receptor (KISS1, GPR54) antagonist. Kisspeptin 234 TFA is an analog of Kisspeptin 10[1].
in vivo

Kisspeptin 234 (1 mg/kg, ip, daily, 28 days) TFA can inhibit the anti-fibrotic effect of Kisspeptin-13 in the bleomycin (BLM)-induced lung fibrosis model of C57BL/6 mice, especially in weight loss, decreased survival rate, increased lung coefficient, and massive infiltration[1].

References[1] Lei Z, et al. Kisspeptin13 inhibits bleomycininduced pulmonary fibrosis through GPR54 in mice. Mol Med Rep. 2019 Aug;20(2):1049-1056. DOI:10.3892/mmr.2019.10341
[2] ANTONIA K ROSEWEIR. Discovery of potent kisspeptin antagonists delineate physiological mechanisms of gonadotropin regulation.[J]. Journal of Neuroscience, 2009, 29 12: 3920-3929. DOI: 10.1523/jneurosci.5740-08.2009
Kisspeptin-234 trifluoroacetate Preparation Products And Raw materials
Tag:Kisspeptin-234 trifluoroacetate(1848962-29-7) Related Product Information
M871 (trifluoroacetate salt) Kisspeptin-10 (zebrafish) (trifluoroacetate salt) Kisspeptin 10 (rat) Kisspeptin-54 (human) (trifluoroacetate salt) HS-024 (trifluoroacetate salt) Kisspeptin-10 (mouse, rat) (TFA)