| Company Name: |
SuZhou Medinoah Co.,LTD. Gold
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| Tel: |
0512-69561983 13914027025 |
| Email: |
zhang_q@medinoah.com |
| Products Intro: |
Product Name:3-(1-oxo-5-(piperazin-1-yl)isoindolin-2-yl)piperidine-2,6-dione hydrochloride
CAS:2222120-31-0
Purity:>95% Package:5g;10g;1kg;10kg;>10kg 大货
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| Company Name: |
Beijing Ouhe Technology Co., Ltd
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| Tel: |
13552068683 13522913783 |
| Email: |
2355560935@qq.com |
| Products Intro: |
Product Name:3-(1-Oxo-5-(piperazin-1-yl)isoindolin-2-yl)piperidine-2,6-dione hydrochloride
CAS:2222120-31-0
Purity:95+% Package:5g
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| Company Name: |
Daicel Chiral Technologies (China)CO.,LTD
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| Tel: |
021-50460086-9 15921403865 |
| Email: |
han_yajun@dctc.daicel.com |
| Products Intro: |
Product Name:3-(1-Oxo-5-(piperazin-1-yl)isoindolin-2-yl)piperidine-2,6-dione Hydrochloride
CAS:2222120-31-0
Purity:95%HPLC Package:250MG;1G Remarks:211959
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| Company Name: |
Shanghai Cuisen Pharmaceutical Technology Co., Ltd.
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| Tel: |
13472757003 |
| Email: |
yongnan.wang@cendrix.cn |
| Products Intro: |
Product Name:3-(1-oxo-5-(piperazin-1-yl)isoindolin-2-yl)piperidine-2,6-dione hydrochloride
CAS:2222120-31-0
Purity:97%hplc Package:100g;1kg Remarks:CS7034
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| | 2,6-Piperidinedione, 3-[1,3-dihydro-1-oxo-5-(1-piperazinyl)-2H-isoindol-2-yl]-, hydrochloride (1:1) Basic information |
| Product Name: | 2,6-Piperidinedione, 3-[1,3-dihydro-1-oxo-5-(1-piperazinyl)-2H-isoindol-2-yl]-, hydrochloride (1:1) | | Synonyms: | 2,6-Piperidinedione, 3-[1,3-dihydro-1-oxo-5-(1-piperazinyl)-2H-isoindol-2-yl]-, hydrochloride (1:1);3-(1-Oxo-5-(piperazin-1-yl)isoindolin-2-yl)piperidine-2,6-dione hydrochloride;2,6-Piperidinedione, 3-[1,3-dihydro-1-oxo-5-(1-piperazinyl)-2H-isoindol-2-yl]-, hydrochloride;3-(l-oxo-5-(piperazin-1-yl)isoindolin-2-yl)piperidine-2, 6-dione hydrochloride;Lenalidomide 5'-piperazine;Lenalidomide 5'-piperazine (hydrochloride) | | CAS: | 2222120-31-0 | | MF: | C17H21ClN4O3 | | MW: | 364.83 | | EINECS: | | | Product Categories: | | | Mol File: | 2222120-31-0.mol | ![2,6-Piperidinedione, 3-[1,3-dihydro-1-oxo-5-(1-piperazinyl)-2H-isoindol-2-yl]-, hydrochloride (1:1) Structure](CAS/20211123/GIF/2222120-31-0.gif) |
| | 2,6-Piperidinedione, 3-[1,3-dihydro-1-oxo-5-(1-piperazinyl)-2H-isoindol-2-yl]-, hydrochloride (1:1) Chemical Properties |
| storage temp. | 2-8°C, sealed storage, away from moisture | | form | Solid | | color | White to off-white | | InChI | InChI=1S/C17H20N4O3.ClH/c22-15-4-3-14(16(23)19-15)21-10-11-9-12(1-2-13(11)17(21)24)20-7-5-18-6-8-20;/h1-2,9,14,18H,3-8,10H2,(H,19,22,23);1H | | InChIKey | CRHGKGZERJKUDG-UHFFFAOYSA-N | | SMILES | O=C1C2=CC=C(N3CCNCC3)C=C2CN1C1CCC(=O)NC1=O.Cl |
| | 2,6-Piperidinedione, 3-[1,3-dihydro-1-oxo-5-(1-piperazinyl)-2H-isoindol-2-yl]-, hydrochloride (1:1) Usage And Synthesis |
| Description | CUN-20310 is a functionalized cereblon ligand for PROTAC research and development; incorporates an E3 ligase ligand with a terminal piperazine for onward chemistry to generate Protein Degraders with rigid linkers. It is part of a range of functionalized tool molecules for PROTAC R&D. This product has no formal name. | | Uses | Lenalidomide 5'-piperazine is a functionalized cerebellar ligand for PROTAC development that binds an E3 ligand to terminal piperazine for subsequent chemical reactions to produce a protein deactivator with a rigid linker[1]. | | IC 50 | Cereblon | | storage | Store at -20°C | | References | [1] Andrew P. Crew, et al. Cereblon ligands and bifunctional compounds comprising the same. WO2019199816A1.2019-10-17. |
| | 2,6-Piperidinedione, 3-[1,3-dihydro-1-oxo-5-(1-piperazinyl)-2H-isoindol-2-yl]-, hydrochloride (1:1) Preparation Products And Raw materials |
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