2-Naphthalenol, 5-chloro-4-[4-(3,8-diazabicyclo[3.2.1]oct-3-yl)-8-fluoro-2-[[(2R,7aS)-2-fluorotetrahydro-1H-pyrrolizin-7a(5H)-yl]methoxy]pyrido[4,3-d]pyrimidin-7-yl]-

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2-Naphthalenol, 5-chloro-4-[4-(3,8-diazabicyclo[3.2.1]oct-3-yl)-8-fluoro-2-[[(2R,7aS)-2-fluorotetrahydro-1H-pyrrolizin-7a(5H)-yl]methoxy]pyrido[4,3-d]pyrimidin-7-yl]- Suppliers list
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2-Naphthalenol, 5-chloro-4-[4-(3,8-diazabicyclo[3.2.1]oct-3-yl)-8-fluoro-2-[[(2R,7aS)-2-fluorotetrahydro-1H-pyrrolizin-7a(5H)-yl]methoxy]pyrido[4,3-d]pyrimidin-7-yl]- Basic information
Product Name:2-Naphthalenol, 5-chloro-4-[4-(3,8-diazabicyclo[3.2.1]oct-3-yl)-8-fluoro-2-[[(2R,7aS)-2-fluorotetrahydro-1H-pyrrolizin-7a(5H)-yl]methoxy]pyrido[4,3-d]pyrimidin-7-yl]-
Synonyms:2-Naphthalenol, 5-chloro-4-[4-(3,8-diazabicyclo[3.2.1]oct-3-yl)-8-fluoro-2-[[(2R,7aS)-2-fluorotetrahydro-1H-pyrrolizin-7a(5H)-yl]methoxy]pyrido[4,3-d]pyrimidin-7-yl]-;KRAS G12D inhibitor 5
CAS:2621928-53-6
MF:C31H31ClF2N6O2
MW:593.07
EINECS:
Product Categories:
Mol File:2621928-53-6.mol
2-Naphthalenol, 5-chloro-4-[4-(3,8-diazabicyclo[3.2.1]oct-3-yl)-8-fluoro-2-[[(2R,7aS)-2-fluorotetrahydro-1H-pyrrolizin-7a(5H)-yl]methoxy]pyrido[4,3-d]pyrimidin-7-yl]- Structure
2-Naphthalenol, 5-chloro-4-[4-(3,8-diazabicyclo[3.2.1]oct-3-yl)-8-fluoro-2-[[(2R,7aS)-2-fluorotetrahydro-1H-pyrrolizin-7a(5H)-yl]methoxy]pyrido[4,3-d]pyrimidin-7-yl]- Chemical Properties
density 1.51±0.1 g/cm3(Predicted)
pka7.92±0.40(Predicted)
Safety Information
MSDS Information
2-Naphthalenol, 5-chloro-4-[4-(3,8-diazabicyclo[3.2.1]oct-3-yl)-8-fluoro-2-[[(2R,7aS)-2-fluorotetrahydro-1H-pyrrolizin-7a(5H)-yl]methoxy]pyrido[4,3-d]pyrimidin-7-yl]- Usage And Synthesis
UsesKRAS G12D inhibitor 5 is a KRAS G12D inhibitor for the potential research of pancreatic cancer.
References[1] Kargbo RB. Targeting KRAS G12D Mutant for the Potential Treatment of Pancreatic Cancer. ACS Med Chem Lett. 2021 Oct 19;12(11):1643-1645. DOI:10.1021/acsmedchemlett.1c00545
2-Naphthalenol, 5-chloro-4-[4-(3,8-diazabicyclo[3.2.1]oct-3-yl)-8-fluoro-2-[[(2R,7aS)-2-fluorotetrahydro-1H-pyrrolizin-7a(5H)-yl]methoxy]pyrido[4,3-d]pyrimidin-7-yl]- Preparation Products And Raw materials
Tag:2-Naphthalenol, 5-chloro-4-[4-(3,8-diazabicyclo[3.2.1]oct-3-yl)-8-fluoro-2-[[(2R,7aS)-2-fluorotetrahydro-1H-pyrrolizin-7a(5H)-yl]methoxy]pyrido[4,3-d]pyrimidin-7-yl]-(2621928-53-6) Related Product Information
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