4-Pyrimidinecarboxamide, 1,6-dihydro-5-hydroxy-6-oxo-2-(2-thienyl)-N-[[4-(trifluoromethyl)phenyl]methyl]-

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4-Pyrimidinecarboxamide, 1,6-dihydro-5-hydroxy-6-oxo-2-(2-thienyl)-N-[[4-(trifluoromethyl)phenyl]methyl]- Suppliers list
Company Name: TargetMol Chemicals Inc.  
Tel: 15002134094
Email: marketing@targetmol.cn
Company Name: TargetMol Chemicals Inc.  
Tel: 13564774135
Email: marketing@targetmol.com

4-Pyrimidinecarboxamide, 1,6-dihydro-5-hydroxy-6-oxo-2-(2-thienyl)-N-[[4-(trifluoromethyl)phenyl]methyl]- manufacturers
4-Pyrimidinecarboxamide, 1,6-dihydro-5-hydroxy-6-oxo-2-(2-thienyl)-N-[[4-(trifluoromethyl)phenyl]methyl]- Basic information
Product Name:4-Pyrimidinecarboxamide, 1,6-dihydro-5-hydroxy-6-oxo-2-(2-thienyl)-N-[[4-(trifluoromethyl)phenyl]methyl]-
Synonyms:4-Pyrimidinecarboxamide, 1,6-dihydro-5-hydroxy-6-oxo-2-(2-thienyl)-N-[[4-(trifluoromethyl)phenyl]methyl]-;pUL89 Endonuclease-IN-2
CAS:519021-48-8
MF:C17H12F3N3O3S
MW:395.36
EINECS:
Product Categories:
Mol File:519021-48-8.mol
4-Pyrimidinecarboxamide, 1,6-dihydro-5-hydroxy-6-oxo-2-(2-thienyl)-N-[[4-(trifluoromethyl)phenyl]methyl]- Structure
4-Pyrimidinecarboxamide, 1,6-dihydro-5-hydroxy-6-oxo-2-(2-thienyl)-N-[[4-(trifluoromethyl)phenyl]methyl]- Chemical Properties
density 1.54±0.1 g/cm3(Predicted)
pka4.50±1.00(Predicted)
Safety Information
MSDS Information
4-Pyrimidinecarboxamide, 1,6-dihydro-5-hydroxy-6-oxo-2-(2-thienyl)-N-[[4-(trifluoromethyl)phenyl]methyl]- Usage And Synthesis
UsespUL89 Endonuclease-IN-2 (Compound 15k) is a potent inhibitor of human cytomegalovirus (HCMV) pUL89 endonuclease with the IC50 of 3.0 μM. Antiviral activities[1].
References[1] Tianyu He, et al. 4,5-Dihydroxypyrimidine Methyl Carboxylates, Carboxylic Acids, and Carboxamides as Inhibitors of Human Cytomegalovirus pUL89 Endonuclease. J Med Chem. 2022 Apr 14;65(7):5830-5849. DOI:10.1021/acs.jmedchem.2c00203
4-Pyrimidinecarboxamide, 1,6-dihydro-5-hydroxy-6-oxo-2-(2-thienyl)-N-[[4-(trifluoromethyl)phenyl]methyl]- Preparation Products And Raw materials
Tag:4-Pyrimidinecarboxamide, 1,6-dihydro-5-hydroxy-6-oxo-2-(2-thienyl)-N-[[4-(trifluoromethyl)phenyl]methyl]-(519021-48-8) Related Product Information
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