1-O-(15-carboxypentadecyl)-2-O-acetylglycero-3-phosphorylcholine manufacturers
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| | 1-O-(15-carboxypentadecyl)-2-O-acetylglycero-3-phosphorylcholine Basic information |
| | 1-O-(15-carboxypentadecyl)-2-O-acetylglycero-3-phosphorylcholine Chemical Properties |
| storage temp. | Store at -20°C | | solubility | DMF: 1 mg/ml; DMSO: 15 mg/ml; Ethanol: 25 mg/ml; PBS (pH 7.2): 10 mg/ml |
| | 1-O-(15-carboxypentadecyl)-2-O-acetylglycero-3-phosphorylcholine Usage And Synthesis |
| Description | PAF C-16 is a naturally occurring phospholipid produced upon stimulation through two distinct pathways known as the “remodeling” and ''de novo'' pathways. It is a potent mediator of neutrophil migration and the production of reactive oxygen species and IL-6. Pathological processes involving PAF include necrotizing enterocolitis, inflammation, asthma, and allergy. PAF C-16 Carboxylic acid is modified with a carboxylic acid group terminating the C-16 alkyl chain. This provides a convenient site for chemical crosslinking. | | Uses | PAF C-16 carboxylic acid (Acetyl-CPGPC) is a phospholipid that possesses haptenic activity causing production of antibodies reactive with platelet-activating factor (PAF)[1]. | | References | [1] K Karasawa, et al. Antibodies to synthetic platelet-activating factor (1-O-alkyl-2-O-acetyl-sn-glycero-3-phosphocholine) analogues with substituents at the sn-2 position. J Biochem. 1991 Nov;110(5):683-7. DOI:10.1093/oxfordjournals.jbchem.a123641 |
| | 1-O-(15-carboxypentadecyl)-2-O-acetylglycero-3-phosphorylcholine Preparation Products And Raw materials |
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