2-Pyridinecarboxylic acid, 5-cyano-1,6-dihydro-3-(4-nitrobenzoyl)-6-oxo-, ethyl ester, compd. with N-methylmethanamine (1:1)

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2-Pyridinecarboxylic acid, 5-cyano-1,6-dihydro-3-(4-nitrobenzoyl)-6-oxo-, ethyl ester, compd. with N-methylmethanamine (1:1) Suppliers list
Company Name: TargetMol Chemicals Inc.  
Tel: 15002134094
Email: marketing@targetmol.cn
Company Name: TargetMol Chemicals Inc.  
Tel: 13564774135
Email: marketing@targetmol.com

2-Pyridinecarboxylic acid, 5-cyano-1,6-dihydro-3-(4-nitrobenzoyl)-6-oxo-, ethyl ester, compd. with N-methylmethanamine (1:1) manufacturers

  • COX-2-IN-14
  • COX-2-IN-14 pictures
  • $1520.00
  • 2026-04-20
  • CAS:2428387-48-6
  • Purity:
  • Supply Ability: 10g
2-Pyridinecarboxylic acid, 5-cyano-1,6-dihydro-3-(4-nitrobenzoyl)-6-oxo-, ethyl ester, compd. with N-methylmethanamine (1:1) Basic information
Product Name:2-Pyridinecarboxylic acid, 5-cyano-1,6-dihydro-3-(4-nitrobenzoyl)-6-oxo-, ethyl ester, compd. with N-methylmethanamine (1:1)
Synonyms:2-Pyridinecarboxylic acid, 5-cyano-1,6-dihydro-3-(4-nitrobenzoyl)-6-oxo-, ethyl ester, compd. with N-methylmethanamine (1:1);COX-2-IN-14
CAS:2428387-48-6
MF:C18H18N4O6
MW:386.36
EINECS:
Product Categories:
Mol File:2428387-48-6.mol
2-Pyridinecarboxylic acid, 5-cyano-1,6-dihydro-3-(4-nitrobenzoyl)-6-oxo-, ethyl ester, compd. with N-methylmethanamine (1:1) Structure
2-Pyridinecarboxylic acid, 5-cyano-1,6-dihydro-3-(4-nitrobenzoyl)-6-oxo-, ethyl ester, compd. with N-methylmethanamine (1:1) Chemical Properties
Safety Information
MSDS Information
2-Pyridinecarboxylic acid, 5-cyano-1,6-dihydro-3-(4-nitrobenzoyl)-6-oxo-, ethyl ester, compd. with N-methylmethanamine (1:1) Usage And Synthesis
UsesCOX-2-IN-14 (compound 2a) is a potent and selective COX-2 (cyclooxygenase-2) inhibitor. COX-2-IN-14 shows effective binding at the active site of COX-2 co-crystal. COX-2-IN-14 exhibits a high level of in vivo anti-inflammatory activity, reducing ear edema and myeloperoxidase (MPO) activity in mice[1].
IC 50COX-2
References[1] Gonalves DS, et al. Synthesis of novel 3,5,6-trisubstituted 2-pyridone derivatives and evaluation for their anti-inflammatory activity. Bioorg Med Chem. 2020 Jun 15;28(12):115549. DOI:10.1016/j.bmc.2020.115549
2-Pyridinecarboxylic acid, 5-cyano-1,6-dihydro-3-(4-nitrobenzoyl)-6-oxo-, ethyl ester, compd. with N-methylmethanamine (1:1) Preparation Products And Raw materials
Tag:2-Pyridinecarboxylic acid, 5-cyano-1,6-dihydro-3-(4-nitrobenzoyl)-6-oxo-, ethyl ester, compd. with N-methylmethanamine (1:1)(2428387-48-6) Related Product Information
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