| Company Name: |
Lynnchem |
| Tel: |
86-(0)29-85992781 17792393971 |
| Email: |
info@lynnchem.com |
| Company Name: |
Novachemistry |
| Tel: |
44-20819178-90 02081917890 |
| Email: |
info@novachemistry.com |
|
| | PD 124895 Basic information |
| Product Name: | PD 124895 | | Synonyms: | PD 124895;4,8,10,14,18,20,22-Heptamethyl-16-hydroxymethyl-5,19-dihydroxy-17-oxo-2,6,8,12,14,22-tetracosahexenedioic acid δ-lactone;Antibiotic CL-1957E;Antibiotic PD-124895;CL-1957E;HydroxyleptoMycin A, CL 1957E, PD 124895, PD 124,895;6-hydroxy-9-(hydroxymethyl)-3,5,7,11,15,17-hexamethyl-19-(3-methyl-6-oxo-2,3-dihydropyran-2-yl)-8-oxononadeca-2,10,12,16,18-pentaenoic acid;2,10,12,16,18-Nonadecapentaenoic acid, 19-(3,6-dihydro-3-methyl-6-oxo-2H-pyran-2-yl)-6-hydroxy-9-(hydroxymethyl)-3,5,7,11,15,17-hexamethyl-8-oxo-, (2E,10E,12E,16Z,18E)- | | CAS: | 107140-30-7 | | MF: | C32H46O7 | | MW: | 542.7 | | EINECS: | | | Product Categories: | | | Mol File: | 107140-30-7.mol |  |
| | PD 124895 Chemical Properties |
| Boiling point | 754.197±60.00 °C(Press: 760.00 Torr)(predicted) | | density | 1.118±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) | | storage temp. | Store at -20°C | | solubility | Soluble in DMSO | | form | Colorless film. | | pka | 5.104±0.33(predicted) |
| | PD 124895 Usage And Synthesis |
| Uses | Kazusamycin B is a minor component of the leptomycin complex produced by some Streptomyces sp.. It is an hydroxylated analogue of leptomycin A, a nuclear export inhibitor. Kazusamycin B displays potent antitumour activity against L1210 and human colon adenocarcinoma, and in vivo activity against P388 lymphocytic leukemia in mice. Kazusamycin B also possesses strong antibacterial and antifungal activity. | | Uses | Kazusamycin B is a minor component of the leptomycin complex that displays anti-bacterial & anti-fungal activity. |
| | PD 124895 Preparation Products And Raw materials |
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