| Company Name: |
Shanghai meikai technology co., ltd
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| Tel: |
021-68689288 15300790979 |
| Email: |
info@mkbio.com.cn |
| Products Intro: |
Product Name:Donidalorsensodium(Synonyms:ISIS-721744;IONIS-PKK-LRX)
CAS:2304701-45-7
Purity:98% Package:100mg;250mg;1g
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| | IONIS-PKK-LRX) Basic information |
| Product Name: | IONIS-PKK-LRX) | | Synonyms: | Donidalorsensodium(Synonyms:ISIS-721744;IONIS-PKK-LRX);Donidalorsen sodium | | CAS: | 2304701-45-7 | | MF: | | | MW: | 0 | | EINECS: | | | Product Categories: | | | Mol File: | Mol File | ![IONIS-PKK-LRX) Structure]() |
| | IONIS-PKK-LRX) Chemical Properties |
| | IONIS-PKK-LRX) Usage And Synthesis |
| Uses | Donidalorsen (sodium) is an antisense oligonucleotide designed to reduce the production of prekallikrein (PKK). PKK plays an important role in the activation of inflammatory mediators associated with acute attacks of Hereditary angioedema (HAE). | | References | [1] Fijen LM, Riedl MA, Bordone L, et al. Inhibition of Prekallikrein for Hereditary Angioedema.N Engl J Med. 2022;386(11):1026-1033. DOI:10.1056/NEJMoa2109329
[2] Valerieva A, Longhurst HJ. Treatment of hereditary angioedema-single or multiple pathways to the rescue.Front Allergy. 2022;3:952233. DOI:10.3389/falgy.2022.952233 |
| | IONIS-PKK-LRX) Preparation Products And Raw materials |
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