YM 16638 manufacturers
- YM 16638
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- $397.00
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2026-05-11
- CAS:104073-72-5
- Purity: 99.18%
- Supply Ability: 10g
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| | YM 16638 Basic information |
| Product Name: | YM 16638 | | Synonyms: | YM 16638;[[5-[[3-(4-Acetyl-3-hydroxy-2-propylphenoxy)propyl]thio]-1,3,4-thiadiazol-2-yl]thio]acetic acid;YM-638;2-[[5-[3-(4-acetyl-3-hydroxy-2-propylphenoxy)propylsulfanyl]-1,3,4-thiadiazol-2-yl]sulfanyl]acetic acid;Acetic acid, 2-[[5-[[3-(4-acetyl-3-hydroxy-2-propylphenoxy)propyl]thio]-1,3,4-thiadiazol-2-yl]thio]-;YM 638|||YM-16638|||YM16638 | | CAS: | 104073-72-5 | | MF: | C18H22N2O5S3 | | MW: | 442.57 | | EINECS: | | | Product Categories: | | | Mol File: | 104073-72-5.mol |  |
| | YM 16638 Chemical Properties |
| Melting point | 129-130 °C | | Boiling point | 682.6±65.0 °C(Predicted) | | density | 1.42±0.1 g/cm3(Predicted) | | pka | 2.87±0.10(Predicted) |
| | YM 16638 Usage And Synthesis |
| Uses | YM-16638 is an orally active leukotriene (LT) antagonist. YM-16638 can inhibit the production of LTC4, LTD4, and LTE4 in guinea pig trachea, with IC50 values of 0.05 μM, 0.16 μM, and 0.096 μM, respectively. YM-16638 has a dose-dependent inhibitory effect on antigen-induced early and late respiratory responses in allergic sheep[1]. | | References | [1] Tomioka K, et al. The effect of an orally active leukotriene (LT) antagonist YM-16638 on antigen-induced early and late airway responses in allergic sheep. Prostaglandins Leukot Essent Fatty Acids. 1989 Apr;36(1):43-7. DOI:10.1016/0952-3278(89)90161-0 |
| | YM 16638 Preparation Products And Raw materials |
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