| Company Name: |
TargetMol Chemicals Inc.
|
| Tel: |
15002134094 |
| Email: |
marketing@targetmol.cn |
| Products Intro: |
Product Name:8(R),9(S)-EET
CAS:129172-62-9
Package:50mg/RMB 13800
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| Company Name: |
Cayman Chemical Company
|
| Tel: |
800-364-9897 |
| Email: |
sales@caymanchem.com |
| Products Intro: |
Product Name:8R(9S)-EET
|
| Company Name: |
Neobioscience Co., Ltd.
|
| Tel: |
4006-800-892 |
| Email: |
info@neobioscience.com |
| Products Intro: |
Product Name:8R(9S)-EET
|
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| | 8(R),9(S)-EET Basic information |
| Product Name: | 8(R),9(S)-EET | | Synonyms: | 8(R),9(S)-EET;5-Heptenoic acid, 7-[(2R,3S)-3-(2Z,5Z)-2,5-undecadien-1-yl-2-oxiranyl]-, (5Z)- | | CAS: | 129172-62-9 | | MF: | C20H32O3 | | MW: | 320.47 | | EINECS: | | | Product Categories: | | | Mol File: | 129172-62-9.mol |  |
| | 8(R),9(S)-EET Chemical Properties |
| Boiling point | 456.210±20.00 °C(Press: 760.00 Torr)(predicted) | | density | 0.983±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) | | solubility | Acetonitrile: Sparingly Soluble: 1-10 mg/ml
Ethanol: Slightly Soluble: 0.1-1 mg/ml | | pka | 4.754±0.10(predicted) |
| | 8(R),9(S)-EET Usage And Synthesis |
| Uses | 8(R),9(S)-EET is an isomer of Epoxyeicosatrienoic acid (HY-113489). 8(R),9(S)-EET processes its metabolism with cytosolic epoxide hydrolase (cEH), with a binding affinity of Km of 41 μM[1]. | | References | [1] Zeldin DC, et al., Metabolism of epoxyeicosatrienoic acids by cytosolic epoxide hydrolase: substrate structural determinants of asymmetric catalysis. Arch Biochem Biophys. 1995 Jan 10;316(1):443-51. DOI:10.1006/abbi.1995.1059
[2] JORGE H. CAPDEVILA. Cytochrome P-450 enzyme-specific control of the regio- and enantiofacial selectivity of the microsomal arachidonic acid epoxygenase.[J]. The Journal of Biological Chemistry, 1990, 24 1: 10865-10871. DOI: 10.1016/s0021-9258(19)38526-6
[3] YONGDE ZHANG. EET homologs potently dilate coronary microvessels and activate BK(Ca) channels.[J]. American journal of physiology. Heart and circulatory physiology, 2001, 280 6 1: H2430-40. DOI: 10.1152/ajpheart.2001.280.6.h2430 |
| | 8(R),9(S)-EET Preparation Products And Raw materials |
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