SHP2-IN-27

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SHP2-IN-27 Suppliers list
Company Name: TargetMol Chemicals Inc.  
Tel: 15002134094
Email: marketing@targetmol.cn
SHP2-IN-27 Basic information
Product Name:SHP2-IN-27
Synonyms:SHP2-IN-27;8-Azabicyclo[3.2.1]octan-3-amine, 8-[7-(4-chloro-2-methyl-2H-indazol-5-yl)-5H-pyrrolo[2,3-b]pyrazin-3-yl]-, (3-endo)-
CAS:2376012-00-7
MF:C21H22ClN7
MW:407.9
EINECS:
Product Categories:
Mol File:2376012-00-7.mol
SHP2-IN-27 Structure
SHP2-IN-27 Chemical Properties
density 1.66±0.1 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)
pka12.23±0.50(predicted)
Safety Information
MSDS Information
SHP2-IN-27 Usage And Synthesis
UsesSHP2-IN-27 (compound 28) is an allosteric inhibitor of tyrosine phosphatase SH2[1].
References[1] Day JEH, et al. Fragment-Based Discovery of Allosteric Inhibitors of SH2 Domain-Containing Protein Tyrosine Phosphatase-2 (SHP2). J Med Chem. 2024 Mar 10. DOI:10.1021/acs.jmedchem.3c02118
SHP2-IN-27 Preparation Products And Raw materials
Tag:SHP2-IN-27(2376012-00-7) Related Product Information
Sodium Stibogluconate SHP836 4-Piperidinamine, 1-[3-(2,3-dichlorophenyl)-1H-pyrazolo[3,4-b]pyrazin-6-yl]-4-methyl- 2-Pyrazinemethanol, 6-[(2-amino-3-chloro-4-pyridinyl)thio]-3-[(3S,4S)-4-amino-3-methyl-2-oxa-8-azaspiro[4.5]dec-8-yl]-5-methyl- SHP2-IN-13 L-Lysine, L-asparaginyl-L-histidyl-L-alanyl-L-seryl-L-seryl-L-valyl-L-prolyl-L-arginyl-L-seryl-L-lysyl-L-isoleucyl-L-leucyl-L-threonyl-L-valyl-L-arginyl-L-valyl-L-isoleucyl-L-leucyl-L-alanyl-L-prolyl-L-tryptophyl-L-lysyl-