| Company Name: |
Shanghai meikai technology co., ltd
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| Tel: |
021-68689288 15300790979 |
| Email: |
info@mkbio.com.cn |
| Products Intro: |
Product Name:Tilsotolimod
CAS:1948266-37-2
Purity:98% Package:100mg;250mg;1g
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| Company Name: |
Biorbyt Ltd.
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| Tel: |
+44 (0)1223 859 353 |
| Email: |
info@biorbyt.com |
| Products Intro: |
Product Name:Tilsotolimod
CAS:1948266-37-2
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| | Tilsotolimod Basic information |
| | Tilsotolimod Chemical Properties |
| | Tilsotolimod Usage And Synthesis |
| Uses | Tilsotolimod is a synthetic Toll-like receptor 9 (TLR9) agonist that has demonstrated antitumor activity in preclinical models. | | References | [1] Karime C, Wang J, Woodhead G, et al. Tilsotolimod: an investigational synthetic toll-like receptor 9 (TLR9) agonist for the treatment of refractory solid tumors and melanoma.Expert Opin Investig Drugs. 2022;31(1):1-13. DOI:10.1080/13543784.2022.2019706
[2] Haymaker C, Johnson DH, Murthy R, et al. Tilsotolimod with Ipilimumab Drives Tumor Responses in Anti-PD-1 Refractory Melanoma.Cancer Discov. 2021;11(8):1996-2013. DOI:10.1158/2159-8290.CD-20-1546
[3] Babiker H, Borazanci E, Subbiah V, et al. Tilsotolimod Exploits the TLR9 Pathway to Promote Antigen Presentation and Type 1 IFN Signaling in Solid Tumors: A Multicenter International Phase I/II Trial (ILLUMINATE-101).Clin Cancer Res. 2022;28(23):5079-5087. DOI:10.1158/1078-0432.CCR-21-4486 |
| | Tilsotolimod Preparation Products And Raw materials |
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