MPO-IN-8

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MPO-IN-8 Suppliers list
Company Name: TargetMol Chemicals Inc.  
Tel: 15002134094
Email: marketing@targetmol.cn
MPO-IN-8 Basic information
Product Name:MPO-IN-8
Synonyms:MPO-IN-8
CAS:62578-87-4
MF:
MW:0
EINECS:
Product Categories:
Mol File:Mol File
MPO-IN-8 Structure
MPO-IN-8 Chemical Properties
Safety Information
MSDS Information
MPO-IN-8 Usage And Synthesis
UsesMPO-IN-8 is an orally active myeloperoxidase (MPO) inhibitor. MPO-IN-8 can inhibit the generation of hypochlorous acid in neutrophils and the release of extracellular traps (NETosis). In mice with gouty arthritis, MPO-IN-8 can reduce swelling, lower peroxidase activity, and decrease IL-1β levels[1].
References[1] Matos IA, et al. Targeting Myeloperoxidase Ameliorates Gouty Arthritis: A Virtual Screening Success Story. J Med Chem. 2024 Jul 25;67(14):12012-12032. DOI:10.1021/acs.jmedchem.4c00721
MPO-IN-8 Preparation Products And Raw materials
Tag:MPO-IN-8(62578-87-4) Related Product Information
ML162 PKUMDL-LC-101-D04 PF-06281355 Hexadecanedioic acid 4H-Pyrrolo[3,2-d]pyrimidin-4-one, 1-[[2-[(1R)-1-aminoethyl]-4-chlorophenyl]methyl]-1,2,3,5-tetrahydro-2-thioxo- Curdione