Uridine-5'-O-triphosphoro-γ-1-(5-sulfonic acid)naphthylamidate (sodium salt)

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Uridine-5'-O-triphosphoro-γ-1-(5-sulfonic acid)naphthylamidate (sodium salt) Basic information
Product Name:Uridine-5'-O-triphosphoro-γ-1-(5-sulfonic acid)naphthylamidate (sodium salt)
Synonyms:Uridine-5'-O-triphosphoro-γ-1-(5-sulfonic acid)naphthylamidate (sodium salt);Uridine-5'-O-triphosphoro-γ-1-(5-sulfonic acid)naphthylamidate (sodium salt)
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MW:0
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Mol File:Mol File
Uridine-5'-O-triphosphoro-γ-1-(5-sulfonic acid)naphthylamidate (sodium salt) Structure
Uridine-5'-O-triphosphoro-γ-1-(5-sulfonic acid)naphthylamidate (sodium salt) Chemical Properties
solubility Water: Soluble
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MSDS Information
Uridine-5'-O-triphosphoro-γ-1-(5-sulfonic acid)naphthylamidate (sodium salt) Usage And Synthesis
DescriptionUridine-5'-O-triphosphoro-γ-1-(5-sulfonic acid)naphthylamidate (UTP-γ-AmNS) is a fluorescent derivative of the nucleotide and dual purinergic P2Y2 and P2Y4 receptor agonist UTP (Item No. 9003530).1 It has been used in high-throughput screening (HTS) assays for inhibitors of bacterial RNA polymerase activity. Upon incorporation of UMP in RNA, γ-AmNS-PPi is released, which has an emission at 465 nm upon excitation at 360 nm and a higher fluorescence intensity than UTP-γ-AmNS.WARNING This product is not for human or veterinary use.
References[1] JYOTHI BHAT . High-Throughput Screening of RNA Polymerase Inhibitors Using a Fluorescent UTP Analog[J]. SLAS Discovery, 2006, 11 8: Pages 968-976. DOI: 10.1177/1087057106291978
Uridine-5'-O-triphosphoro-γ-1-(5-sulfonic acid)naphthylamidate (sodium salt) Preparation Products And Raw materials
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