N-[1-(3-Benzyl-7-chloro-4-oxo-3,4-dihydro-quinazolin-2-yl)-propyl]-4-bromo-N-(3-dimethylamino-propyl)-benzamide

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N-[1-(3-Benzyl-7-chloro-4-oxo-3,4-dihydro-quinazolin-2-yl)-propyl]-4-bromo-N-(3-dimethylamino-propyl)-benzamide manufacturers

  • CK0106023
  • CK0106023 pictures
  • $2500.00
  • 2026-04-20
  • CAS:336115-72-1
  • Purity:
  • Supply Ability: 10g
N-[1-(3-Benzyl-7-chloro-4-oxo-3,4-dihydro-quinazolin-2-yl)-propyl]-4-bromo-N-(3-dimethylamino-propyl)-benzamide Basic information
Product Name:N-[1-(3-Benzyl-7-chloro-4-oxo-3,4-dihydro-quinazolin-2-yl)-propyl]-4-bromo-N-(3-dimethylamino-propyl)-benzamide
Synonyms:N-[1-(3-Benzyl-7-chloro-4-oxo-3,4-dihydro-quinazolin-2-yl)-propyl]-4-bromo-N-(3-dimethylamino-propyl)-benzamide;CK0106023;N-[1-(3-Benzyl-7-chloro-4-oxo-quinazolin-2-yl)propyl]-4-bromo-N-[3-(dimethylamino)propyl]benzamide;Benzamide, 4-bromo-N-[1-[7-chloro-3,4-dihydro-4-oxo-3-(phenylmethyl)-2-quinazolinyl]propyl]-N-[3-(dimethylamino)propyl]-
CAS:336115-72-1
MF:C30H32BrClN4O2
MW:595.96
EINECS:
Product Categories:
Mol File:336115-72-1.mol
N-[1-(3-Benzyl-7-chloro-4-oxo-3,4-dihydro-quinazolin-2-yl)-propyl]-4-bromo-N-(3-dimethylamino-propyl)-benzamide Structure
N-[1-(3-Benzyl-7-chloro-4-oxo-3,4-dihydro-quinazolin-2-yl)-propyl]-4-bromo-N-(3-dimethylamino-propyl)-benzamide Chemical Properties
Boiling point 717.0±70.0 °C(Predicted)
density 1.31±0.1 g/cm3(Predicted)
pka9.33±0.28(Predicted)
Safety Information
MSDS Information
N-[1-(3-Benzyl-7-chloro-4-oxo-3,4-dihydro-quinazolin-2-yl)-propyl]-4-bromo-N-(3-dimethylamino-propyl)-benzamide Usage And Synthesis
UsesCK0106023 is a potent and specific allosteric inhibitor of KSP with a Ki value of 12 nM, showing antitumor activity. CK0106023 causes mitotic arrest and growth inhibition in several tumor cell lines. CK0106023 exhibits antitumor activity in tumor-bearing mice[1][2].
References[1] You-Ling Fan. End-capped polyarylene polyethers, articles made therefrom and process for preparing such polyarylene polyethers. EP0106023B1. 1988 March 30.
[2] Sakowicz R, et al. Antitumor activity of a kinesin inhibitor. Cancer Res. 2004 May 1;64(9):3276-80. DOI:10.1158/0008-5472.can-03-3839
N-[1-(3-Benzyl-7-chloro-4-oxo-3,4-dihydro-quinazolin-2-yl)-propyl]-4-bromo-N-(3-dimethylamino-propyl)-benzamide Preparation Products And Raw materials
Tag:N-[1-(3-Benzyl-7-chloro-4-oxo-3,4-dihydro-quinazolin-2-yl)-propyl]-4-bromo-N-(3-dimethylamino-propyl)-benzamide(336115-72-1) Related Product Information
3-Benzyl-2-propyl-3H-quinazolin-4-one 3-Methyl-2-(1-methylaminoethyl)-3H-quinazolin-4-one N-[1-(3-Benzyl-7-chloro-4-oxo-3,4-dihydro-quinazolin-2-yl)-propyl]-4-bromo-N-(3-dimethylamino-propyl)-benzamide 2-Quinazolineacetamide, α-[(3-aminopropyl)(4-methylbenzoyl)amino]-7-chloro-3,4-dihydro-N,N-dimethyl-4-oxo-3-(phenylmethyl)- Ispinesib 3-benzyl-7-chloro-2-isobutylquinazolin-4(3H)-one