8-Chloro-3a,4-dihydro-6-(2-fluorophenyl)-1-methyl-3H-imidazo[1,5-a][1,4]benzo-diazepine

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8-Chloro-3a,4-dihydro-6-(2-fluorophenyl)-1-methyl-3H-imidazo[1,5-a][1,4]benzo-diazepine Basic information
Product Name:8-Chloro-3a,4-dihydro-6-(2-fluorophenyl)-1-methyl-3H-imidazo[1,5-a][1,4]benzo-diazepine
Synonyms:8-CHLOOR-6-(2-FLUORFENYL)-1-METHYL-3A,4-DIHYDRO-3H-IMIDAZO[1,5-A][1,4]BENZODIAZEPINE;Midazolam Impurity 9(Midazolam EP Impurity I);8-Chloro-6-(2-fluorophenyl)-1-methyl-3a,4-dihydro-3H-benzo[f]imidazo[1,5-a][1,4]diazepine;8-chloro-6-(2-fluorophenyl)-3a,4-dihydro-1-methyl-3H-Imidazo[1,5-a][1,4]benzodiazepine;3H-Imidazo[1,5-a][1,4]benzodiazepine, 8-chloro-6-(2-fluorophenyl)-3a,4-dihydro-1-methyl-;8-Chloro-6-(2-fluorophenyl)-3a,4-dihydro-1-methyl-3H-Imidazo[1,5-a][1,4]benzodiazepine (>90%);(3aRS)-8-Chloro-6-(2-fluorophenyl)-1-methyl-3a,4-dihydro-3H-imidazo[1,5-a][1,4]benzodiazepin;1H,3H-Naphtho[1,8-cd]pyran-1,3-dione,6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-3-yl)-
CAS:59467-69-5
MF:C18H15ClFN3
MW:327.78
EINECS:
Product Categories:
Mol File:59467-69-5.mol
8-Chloro-3a,4-dihydro-6-(2-fluorophenyl)-1-methyl-3H-imidazo[1,5-a][1,4]benzo-diazepine Structure
8-Chloro-3a,4-dihydro-6-(2-fluorophenyl)-1-methyl-3H-imidazo[1,5-a][1,4]benzo-diazepine Chemical Properties
Melting point 144-146 °C(Solv: ethyl acetate (141-78-6))
Boiling point 453.9±55.0 °C(Predicted)
density 1.36±0.1 g/cm3(Predicted)
solubility Chloroform (Sparingly), DMSO (Slightly), Methanol (Slightly)
form Solid
pka10.88±0.40(Predicted)
color Off-White to Yellow
Safety Information
MSDS Information
8-Chloro-3a,4-dihydro-6-(2-fluorophenyl)-1-methyl-3H-imidazo[1,5-a][1,4]benzo-diazepine Usage And Synthesis
Uses8-Chloro-6-(2-fluorophenyl)-3a,4-dihydro-1-methyl-83H-Imidazo[1,5-a][1,4]benzodiazepine is an impurity of Midazolam (M343000), a drug used for the treatment of acute seizures and is also known to exhibit activities as an anticonvulsant, sedative, and hypnotic.
8-Chloro-3a,4-dihydro-6-(2-fluorophenyl)-1-methyl-3H-imidazo[1,5-a][1,4]benzo-diazepine Preparation Products And Raw materials
Preparation ProductsMidazolam-->8-Chloro-1-methyl-6-phenyl-4H-Imidazo[1,5-a][1,4]benzodiazepine
Tag:8-Chloro-3a,4-dihydro-6-(2-fluorophenyl)-1-methyl-3H-imidazo[1,5-a][1,4]benzo-diazepine(59467-69-5) Related Product Information
Chlorine dioxide 5,6-Dihydro Midazolam 8-Chloro-6-(2-fluorophenyl)-1-methyl-6H-Imidazo[1,5-a][1,4]benzodiazepine 8-chloro-6-(o-fluorophenyl)-1-methyl-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylic acid 8-Chloro-1-methyl-6-phenyl-4H-Imidazo[1,5-a][1,4]benzodiazepine 6-Chloro-2-methyl-4-(2-fluorophenyl)quinazoline 8-CHLORO-3A,4-DIHYDRO-6-(2-FLUOROPHENYL)-1-METHYL-3H-IMIDAZO[1,5-A][1,4]BENZO-DIAZEPINE Midazolam