6-Isopropoxy-9-xanthone-2-carboxylic acid

6-Isopropoxy-9-xanthone-2-carboxylic acid Suppliers list
Company Name: 3B Pharmachem (Wuhan) International Co.,Ltd.  
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Email: 3bsc@sina.com
Company Name: Guangzhou Isun Pharmaceutical Co., Ltd  
Tel: 020-39119399 18927568969
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Company Name: Bide Pharmatech Ltd.  
Tel: 400-164-7117 18317119277
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Company Name: Shanghai Lollane Biological Technology Co.,Ltd.  
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6-Isopropoxy-9-xanthone-2-carboxylic acid manufacturers

  • AH 6809
  • AH 6809 pictures
  • $61.00
  • 2026-08-03
  • CAS:33458-93-4
  • Purity: 97.59%
  • Supply Ability: 10g
  • AH 6809
  • AH 6809 pictures
  • $61.00
  • 2026-08-03
  • CAS:33458-93-4
  • Purity: 97.59%
  • Supply Ability: 10g
6-Isopropoxy-9-xanthone-2-carboxylic acid Basic information
Product Name:6-Isopropoxy-9-xanthone-2-carboxylic acid
Synonyms:AH 6809;6-(1-Methylethoxy)-9-oxo-9H-xanthene-2-carboxylic acid;6-Isopropoxy-9-oxo-9H-xanthene-2-carboxylic acid;AH6809;AH-6809;9H-Xanthene-2-carboxylic acid, 6-(1-methylethoxy)-9-oxo-;Prostaglandin Receptor,AH-6809,inhibit,Inhibitor,AH6809,AH 6809;9-oxo-6-(propan-2-yloxy)-9H-xanthene-2-carboxylic acid;AH 6809, EP1 and EP2 antagonist
CAS:33458-93-4
MF:C17H14O5
MW:298.29
EINECS:
Product Categories:
Mol File:33458-93-4.mol
6-Isopropoxy-9-xanthone-2-carboxylic acid Structure
6-Isopropoxy-9-xanthone-2-carboxylic acid Chemical Properties
storage temp. Sealed in dry,Room Temperature
solubility ethanol: 2.5 mg/mL, soluble
form crystalline solid or supercooled liquid
color White
Stability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 6 months.
InChI1S/C17H14O5/c1-9(2)21-11-4-5-12-15(8-11)22-14-6-3-10(17(19)20)7-13(14)16(12)18/h3-9H,1-2H3,(H,19,20)
InChIKeyAQFFXPQJLZFABJ-UHFFFAOYSA-N
SMILESCC(C)Oc1ccc2c(Oc3ccc(cc3C2=O)C(O)=O)c1
Safety Information
WGK Germany 3
Storage Class11 - Combustible Solids
MSDS Information
6-Isopropoxy-9-xanthone-2-carboxylic acid Usage And Synthesis
DescriptionAH 6809 is an EP and DP receptor antagonist with nearly equal affinity for the cloned human EP1, EP2, EP3-III, and DP1 receptors. AH 6809 blocks the PGE2-induced accumulation of cAMP in COS cells transfected with the human EP2 receptor. It also blocks the accumulation of Ca2+ in Xenopus oocytes expressing the human EP1 receptor. In the human and guinea pig, the activity profile of AH 6809 is similar to that of SC-19220, but it is somewhat more potent. In the mouse, AH 6809 has the highest affinity for the EP2 receptor, but also acts as a weak ligand at the murine EP1 and DP1 receptors. In whole human platelets, AH 6809 is an effective antagonist of the antiaggregatory actions of PGD2, but not PGI2, with an EC50 of about 5 x 10−5 M.
UsesAH-6809 is a prostaglandin E2 receptor antagonist.
DefinitionChEBI: 9-oxo-6-propan-2-yloxy-2-xanthenecarboxylic acid is a member of xanthones.
Biological ActivityAntagonist at prostaglandin EP 1 (pA 2 = 6.8 ) and EP 2 (K i = 350 nM) receptors. Also weakly inhibits DP receptors (pA 2 = 4.45).
storageStore at RT
References[1] LANDON K. Prostaglandins and Related Substances. A Practical Approach[J]. Journal of Clinical Pathology, 1988, 6 1: 359-359. DOI:10.1136/jcp.41.3.359-b
6-Isopropoxy-9-xanthone-2-carboxylic acid Preparation Products And Raw materials
Tag:6-Isopropoxy-9-xanthone-2-carboxylic acid(33458-93-4) Related Product Information
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