| Company Name: |
Perfect mRNA |
| Tel: |
4006682586 15252998975 |
| Email: |
rd@perfectmRNA.com |
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| Product Name: | HUMAN IL-5 | | Synonyms: | IL-5, HUMAN;INTERLEUKIN-5;INTERLEUKIN-5, HUMAN;INTERLEUKIN-5, HUMAN, RECOMBINANT;INTERLEUKIN-5, HUMAN, RECOMBINANT, SPODOPTERA FRUGIPERDA;HUMAN IL-5;HUMAN INTERLEUKIN-5;HUMAN BCDFII | | CAS: | | | MF: | | | MW: | 0 | | EINECS: | | | Product Categories: | | | Mol File: | Mol File | ![HUMAN IL-5 Structure]() |
| | HUMAN IL-5 Chemical Properties |
| storage temp. | −20°C | | form | lyophilized powder | | color | off-white to yellow | | biological source | human |
| WGK Germany | 3 | | Storage Class | 11 - Combustible Solids |
| | HUMAN IL-5 Usage And Synthesis |
| Uses | IL-5 is a hematopoietic growth factor that stimulates the proliferation and activation of eosinophils. Produced by mast cells, T cells, and eosinophils, IL-5 plays an important role in inducing cell-mediated immunity against parasitic infections and certain tumors. Elevated levels of IL-5 lead to Eosinophilia, which may result in the induction of asthma and other allergic diseases. Human and murine IL-5 is cross-species reactive. Recombinant human IL-5 is a 26.0 kDa disulfide-linked homodimeric protein containing two 116 amino acid chains. | | Biological Activity | IL-5 is a hematopoietic growth factor th at stimulates the proliferation and activation of eosinophils. Recombinant human IL-5 is a 26.0 kDa disulfide-linked homodimeric protein containing two 116 amino acid chains. | | Description | Interleukin-5 Human Recombinant produced in E.Coli is a dimeric, non-glycosylated polypeptide chain containing two 113 amino acids chains, and having a molecular mass of 26522.84 Dalton. The IL-5 is purified by proprietary chromatographic techniques. | | Source | Escherichia Coli | | Background | The protein encoded by this gene is a cytokine that acts as a growth and differentiation factor for both B cells and eosinophils. This cytokine is a main regulator of eosinopoiesis, eosinophil maturation and activation. The elevated production of this cytokine is reported to be related to asthma or hypereosinophilic syndromes. The receptor of this cytokine is a heterodimer, whose beta subunit is shared with the receptors for interleukine 3 (IL3) and colony stimulating factor 2 (CSF2/GM-CSF). This gene, together with those for interleukin 4 (IL4), interleukin 13 (IL13), and CSF2, form a cytokine gene cluster on chromosome 5. This cytokine, IL4, and IL13 are found to be regulated coordinately by long-range regulatory elements spread over 120 kilobases on chromosome 5q31. |
| | HUMAN IL-5 Preparation Products And Raw materials |
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