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| | (1-pentyl-1H-indol-3-yl) (2, 2, 3, 3-tetraMethyl-cyclopropyl) Methanone Basic information |
| Product Name: | (1-pentyl-1H-indol-3-yl) (2, 2, 3, 3-tetraMethyl-cyclopropyl) Methanone | | Synonyms: | (1-pentyl-1H-indol-3-yl) (2, 2, 3, 3-tetraMethyl-cyclopropyl) Methanone;(1-Pentyl-1H-indol-3-yl)(2,2,3,3-tetraMethylcycl;(1-pentylindol-3-yl)-(2,2,3,3-tetraMethylcyclopropyl)Methanone;KM-X1;MN-001;TMCP-018;YX-17;UR-144((1-pentyl-1H-indol-3-yl) (2, 2, 3, 3-tetraMethyl-cyclopropyl) Methanone) | | CAS: | 1199943-44-6 | | MF: | C21H29NO | | MW: | 311.46 | | EINECS: | 200-659-6 | | Product Categories: | Research Chemical;Cannabinoids.;Food additives | | Mol File: | 1199943-44-6.mol |  |
| | (1-pentyl-1H-indol-3-yl) (2, 2, 3, 3-tetraMethyl-cyclopropyl) Methanone Chemical Properties |
| Boiling point | 426.6±18.0 °C(Predicted) | | density | 1.03 | | storage temp. | -20°C | | solubility | DMF: 30 mg/ml
DMSO: 30 mg/ml
Ethanol: 30 mg/ml | | form | A neat solid |
| | (1-pentyl-1H-indol-3-yl) (2, 2, 3, 3-tetraMethyl-cyclopropyl) Methanone Usage And Synthesis |
| Description | UR-144 (Item No. ISO00055) is an analytical reference material categorized as a synthetic cannabinoid. It has been found in Spice/K2-type herbal blends. UR-144 is regulated as a Schedule I compound in the United States. This product is intended for research and forensic applications. | | Uses | (1-Pentyl-1H-indol-3-yl)(2,2,3,3-tetramethylcyclopropyl)methanone is an Indol-3-ylcycloalkyl Ketone with high affinity for the CB2 cannabinoid receptor. Tetramethylcyclopropyl group was found to lead to high affinity CB2 agonists. Synthetic Cannabinoids | | References | [1] JENNIFER M. FROST*. Indol-3-ylcycloalkyl Ketones: Effects of N1 Substituted Indole Side Chain Variations on CB2 Cannabinoid Receptor Activity[J]. Journal of Medicinal Chemistry, 2009, 53 1: 295-315. DOI: 10.1021/jm901214q
[2] KATHRYN A. SEELY . Forensic investigation of K2, Spice, and “bath salt” commercial preparations: A three-year study of new designer drug products containing synthetic cannabinoid, stimulant, and hallucinogenic compounds[J]. Forensic science international, 2013, 233 1: Pages 416-422. DOI: 10.1016/j.forsciint.2013.10.002
[3] BYUNGSUK CHO . Simultaneous determination of synthetic cannabinoids and their metabolites in human hair using LC-MS/MS and application to human hair[J]. Forensic science international, 2020, 306: Article 110058. DOI: 10.1016/j.forsciint.2019.110058
[4] THOMAS B, LEFEVER T, CORTES R A, et al. Thermolytic Degradation of Synthetic Cannabinoids: Chemical Exposures and Pharmacological Consequences[J]. The Journal of Pharmacology and Experimental Therapeutics, 2017, 9 1: 0. DOI: 10.1124/jpet.116.238717 |
| | (1-pentyl-1H-indol-3-yl) (2, 2, 3, 3-tetraMethyl-cyclopropyl) Methanone Preparation Products And Raw materials |
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