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| | (4-Bromo-2-formylphenoxy)acetic acid Basic information |
| Product Name: | (4-Bromo-2-formylphenoxy)acetic acid | | Synonyms: | AKOS B005879;2-(4-bromo-2-formylphenoxy)acetic acid;2-(4-bromo-2-methanoyl-phenoxy)ethanoic acid;Acetic acid, 2-(4-bromo-2-formylphenoxy)-;3-Pyridinecarboxylicacid,2,7-dimethyl-,methylester;(4-Bromo-2-formylphenoxy)acetic acid | | CAS: | 24589-89-7 | | MF: | C9H7BrO4 | | MW: | 259.05 | | EINECS: | | | Product Categories: | | | Mol File: | 24589-89-7.mol |  |
| | (4-Bromo-2-formylphenoxy)acetic acid Chemical Properties |
| Boiling point | 413.6±30.0 °C(Predicted) | | density | 1.699±0.06 g/cm3(Predicted) | | storage temp. | under inert gas (nitrogen or Argon) at 2-8°C | | pka | 2.96±0.10(Predicted) |
| Hazard Codes | Xn | | Risk Statements | 22 | | HazardClass | IRRITANT |
| | (4-Bromo-2-formylphenoxy)acetic acid Usage And Synthesis |
| Synthesis | Ethyl (4-bromo-2-formylphenoxy)acetate (60 g, 0.209 mol) was added to a mixture of LiOH (7.5 g, 0.31 mol), THF (250 mL) and water (100 mL) and stirred for 24 h at room temperature. Upon completion of the reaction, the reaction mixture was concentrated under reduced pressure and the residue was acidified to pH=2 with 1.5 N HCl. The resulting solid precipitate was filtered and dried to afford (4-bromo-2-formylphenoxy)acetic acid (50 g, 94% yield). | | References | [1] Patent: WO2004/7491, 2004, A1. Location in patent: Page 51
[2] Organic Letters, 2015, vol. 17, # 23, p. 5824 - 5827
[3] European Journal of Medicinal Chemistry, 1999, vol. 34, # 12, p. 1061 - 1070 |
| | (4-Bromo-2-formylphenoxy)acetic acid Preparation Products And Raw materials |
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