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(R)-1-(3,4-dimethoxybenzyl)-6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinoline

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(R)-1-(3,4-dimethoxybenzyl)-6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinoline Basic information
Product Name:(R)-1-(3,4-dimethoxybenzyl)-6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinoline
Synonyms:(1R)-1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-2-methyl-3,4-dihydro-1H-isoquinoline;(R)-1-(3,4-dimethoxybenzyl)-;cis-Atracurium EP Impurity C;Cisatracurium Besilate EP Impurity C;AtracuriuM Besylate iMpurity C;Cisatracurium Besilate EP Impurity C (R-Laudanosine);Isoquinoline, 1-[(3,4-dimethoxyphenyl)methyl]-1,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl-, (1R)-;(R)-1-(3,4-dimethoxybenzyl)-6,7-dimethoxy-2,2-dimethyl-1,2,3,4-tetrahydroisoquinolin-2-ium
CAS:85-63-2
MF:C21H27NO4
MW:357.44
EINECS:
Product Categories:
Mol File:85-63-2.mol
(R)-1-(3,4-dimethoxybenzyl)-6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinoline Structure
(R)-1-(3,4-dimethoxybenzyl)-6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinoline Chemical Properties
solubility Chloroform (Slightly), DMSO (Slightly, Sonicated), Ethanol (Slightly), Methanol
form Solid
color White to Off-White
Safety Information
MSDS Information
(R)-1-(3,4-dimethoxybenzyl)-6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinoline Usage And Synthesis
Uses(R)-Laudanosine is an isomer of (S)-Laudanosine (L178525), a metabolite of the neuromuscular-blocking drugs Atracurium (A794500) and Cisatracurium (C496700) with potentially toxic systemic effects. It crosses the blood-brain barrier and may cause excitement and seizure activity.
DefinitionChEBI: (R)-laudanosine is a benzylisoquinoline alkaloid that is (R)-tetrahydropapaverine in which the amino hydrogen has been replaced by a methyl group It is a polyether, a benzylisoquinoline alkaloid, a benzyltetrahydroisoquinoline, an aromatic ether and a tertiary amino compound. It is functionally related to a (R)-tetrahydropapaverine. It is a conjugate base of a (R)-laudanosine(1+).
Tag:(R)-1-(3,4-dimethoxybenzyl)-6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinoline(85-63-2) Related Product Information
Cisatracurium Besilate EP Impurity T Iodide Atracurium Impurity 1 Cisatracurium Besilate EP Impurity W Iodide (Mixture of Diastereomers) Cisatracurium Besilate EP Impurity N and O Iodide (Mixture of Diastereomers) Cisatracurium Besilate EP Impurity S Iodide Atracurium Impurity 8 Cisatracurium Besilate EP Impurity K Iodide (Mixture of Diastereomers) Cisatracurium Besilate EP Impurity U Iodide AtracuriuM IMpurity V Cisatracurium besylate Cisatracurium Besilate EP Impurity M Iodide Cisatracurium Besilate EP Impurity V Iodide Cis-Quaternary Acid Isoquinolinium, 2-[3-[[5-(acetyloxy)pentyl]oxy]-3-oxopropyl]-1-[(3,4-dimethoxyphenyl)methyl]-1,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl-, (1R,2R)- 2(1H)-Isoquinolinepropanoic acid,1-[(3,4-dimethoxyphenyl)methyl]-3,4-dihydro-6,7-dimethoxy-, 1,5-pentanediyl ester, (R*,R*)-(-)-, ethanedioate Cisatracurium Besilate Impurity 13 Cisatracurium Besilate Impurity 9 Cisatracurium Besilate Impurity 15