[2-(Diethoxy-phosphorylamino)-ethyl]-phosphoramidic acid diethyl ester

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[2-(Diethoxy-phosphorylamino)-ethyl]-phosphoramidic acid diethyl ester Basic information
Product Name:[2-(Diethoxy-phosphorylamino)-ethyl]-phosphoramidic acid diethyl ester
Synonyms:[2-(Diethoxy-phosphorylamino)-ethyl]-phosphoramidic acid diethyl ester;C2-Bis-phosphoramidic acid diethyl ester;Phosphoramidic acid, N,N'-1,2-ethanediylbis-, P,P,P',P'-tetraethyl ester
CAS:34008-16-7
MF:C10H26N2O6P2
MW:332.27
EINECS:
Product Categories:
Mol File:34008-16-7.mol
[2-(Diethoxy-phosphorylamino)-ethyl]-phosphoramidic acid diethyl ester Structure
[2-(Diethoxy-phosphorylamino)-ethyl]-phosphoramidic acid diethyl ester Chemical Properties
Melting point 80-82 °C
Boiling point 380.2±52.0 °C(Predicted)
density 1.165±0.06 g/cm3(Predicted)
pka1.11±0.70(Predicted)
Safety Information
MSDS Information
[2-(Diethoxy-phosphorylamino)-ethyl]-phosphoramidic acid diethyl ester Usage And Synthesis
UsesC2-Bis-phosphoramidic acid diethyl ester is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].
IC 50Alkyl-Chain
References[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
[2-(Diethoxy-phosphorylamino)-ethyl]-phosphoramidic acid diethyl ester Preparation Products And Raw materials
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