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CATHEPSIN G INHIBITOR I manufacturers
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| | CATHEPSIN G INHIBITOR I Basic information |
| | CATHEPSIN G INHIBITOR I Chemical Properties |
| Boiling point | 912.0±75.0 °C(Predicted) | | density | 1.40±0.1 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | Soluble in DMSO | | pka | 1.51±0.10(Predicted) | | form | Solid | | color | White to off-white | | Sensitive | Light Sensitive | | InChIKey | GNOZQRKYZJSIPZ-UHFFFAOYSA-N | | SMILES | [P](=O)(O)(O)C(c5c6c(ccc5)cccc6)C(=O)c1cc2c(cc1C(=O)N(C3CCN(CC3)C(=O)c4ccccc4)C)cccc2 |
| WGK Germany | WGK 1 | | Storage Class | 11 - Combustible Solids |
| | CATHEPSIN G INHIBITOR I Usage And Synthesis |
| Description | Cathepsin G inhibitor I is a potent and selective inhibitor of cathepsin G (IC50 = 53 nM). It weakly inhibits or has no effect on related proteases, including chymotrypsin, thrombin, plasmin, trypsin, tryptase, and elastase. | | Uses | Cathepsin G inhibitor I is a potent and selective inhibitor of cathepsin G. | | target | cathepsins G | | references | [1] greco mn, hawkins mj, powell et, almond hr jr, corcoran tw, de garavilla l, kauffman ja, recacha r, chattopadhyay d, andrade-gordon p, maryanoff be. nonpeptide inhibitors of cathepsin g: optimization of a novel beta-ketophosphonic acid lead by structure-based drug design. j am chem soc. 2002;124(15):3810-1. |
| | CATHEPSIN G INHIBITOR I Preparation Products And Raw materials |
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