3-Piperidinamine,N,4-dimethyl-1-(phenylmethyl)-,hydrochloride (1:2),(3S,4R)- manufacturers
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| | 3-Piperidinamine,N,4-dimethyl-1-(phenylmethyl)-,hydrochloride (1:2),(3S,4R)- Basic information |
| Product Name: | 3-Piperidinamine,N,4-dimethyl-1-(phenylmethyl)-,hydrochloride (1:2),(3S,4R)- | | Synonyms: | Tofacitinib-3;3-Piperidinamine,N,4-dimethyl-1-(phenylmethyl)-,hydrochloride (1:2),(3S,4R)-;Tofacitinib impurity 2/(3S,4R)-1-benzyl-N,4-dimethylpiperidin-3-amine dihydrochloride;(3S,4R)-1-Benzyl-N,4-dimethylpiperidin-3-aminehydrochloride;Azilsartan medoxomil impurity349;Tofacitinib Impurity 03;Tofatinib Impurity 34（HCI);Non-corresponding isomer impurity 1 | | CAS: | 1821769-41-8 | | MF: | C14H23ClN2 | | MW: | 254.8 | | EINECS: | | | Product Categories: | | | Mol File: | 1821769-41-8.mol |  |
| | 3-Piperidinamine,N,4-dimethyl-1-(phenylmethyl)-,hydrochloride (1:2),(3S,4R)- Chemical Properties |
| InChI | InChI=1/C14H22N2.ClH/c1-12-8-9-16(11-14(12)15-2)10-13-6-4-3-5-7-13;/h3-7,12,14-15H,8-11H2,1-2H3;1H/t12-,14-;/s3 | | InChIKey | FVRZQLQXDPJADE-JAUJFHBUNA-N | | SMILES | C(C1C=CC=CC=1)N1CC[C@@H](C)[C@H](NC)C1.Cl |&1:10,12,r| |
| | 3-Piperidinamine,N,4-dimethyl-1-(phenylmethyl)-,hydrochloride (1:2),(3S,4R)- Usage And Synthesis |
| Uses | (3S,4R)-1-Benzyl-N,4-dimethylpiperidin-3-amine Dihydrochloride is the hydrochloride salt of (3S,4R)-1-Benzyl-N,4-dimethylpiperidin-3-amine (B276220) which is an intermediate in the synthesis of (3S,4R)-Tofacitinib (T528010). (3S,4R)-Tofacitinib is an enantiopure stereoisomer of the drug, Janus kinase 3(Jak3) inhibitor (CP-690,550) that has been found to inhibit selected members of the STE7 and STE20 subfamily of kinases. |
| | 3-Piperidinamine,N,4-dimethyl-1-(phenylmethyl)-,hydrochloride (1:2),(3S,4R)- Preparation Products And Raw materials |
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