m-PEG3-S-PEG3-t-butyl ester

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m-PEG3-S-PEG3-t-butyl ester manufacturers

m-PEG3-S-PEG3-t-butyl ester Basic information
Product Name:m-PEG3-S-PEG3-t-butyl ester
Synonyms:m-PEG3-S-PEG3-t-butyl ester;m-PEG3-S-PEG3-Boc;4,7,10,16,19,22-Hexaoxa-13-thiatricosanoic acid, 1,1-dimethylethyl ester
CAS:2055040-96-3
MF:C20H40O8S
MW:440.59
EINECS:
Product Categories:
Mol File:2055040-96-3.mol
m-PEG3-S-PEG3-t-butyl ester Structure
m-PEG3-S-PEG3-t-butyl ester Chemical Properties
Boiling point 496.6±45.0 °C(Predicted)
density 1.063±0.06 g/cm3(Predicted)
Safety Information
MSDS Information
m-PEG3-S-PEG3-t-butyl ester Usage And Synthesis
Descriptionm-PEG3-S-PEG3-t-butyl ester is a PEG linker containing a t-butyl ester moiety. The t-butyl ester can be removed under acidic conditions. The hydrophilic PEG spacer increases solubility in aqueous media.
Usesm-PEG3-S-PEG3-Boc is a PEG- and Alkyl/ether -based PROTAC linker can be used in the synthesis of PROTACs[1].
IC 50PEGs; Alkyl/ether
References[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562. DOI:10.1016/j.ebiom.2018.09.005
m-PEG3-S-PEG3-t-butyl ester Preparation Products And Raw materials
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