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| | m-PEG3-S-PEG3-t-butyl ester Basic information |
| | m-PEG3-S-PEG3-t-butyl ester Chemical Properties |
| Boiling point | 496.6±45.0 °C(Predicted) | | density | 1.063±0.06 g/cm3(Predicted) |
| | m-PEG3-S-PEG3-t-butyl ester Usage And Synthesis |
| Description | m-PEG3-S-PEG3-t-butyl ester is a PEG linker containing a t-butyl ester moiety. The t-butyl ester can be removed under acidic conditions. The hydrophilic PEG spacer increases solubility in aqueous media. | | Uses | m-PEG3-S-PEG3-Boc is a PEG- and Alkyl/ether -based PROTAC linker can be used in the synthesis of PROTACs[1]. | | IC 50 | PEGs; Alkyl/ether | | References | [1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562. DOI:10.1016/j.ebiom.2018.09.005 |
| | m-PEG3-S-PEG3-t-butyl ester Preparation Products And Raw materials |
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