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| | 2',7'-Dichlorofluorescin diacetate Basic information |
| Product Name: | 2',7'-Dichlorofluorescin diacetate | | Synonyms: | diacetyldichlorofluorescein;2',7'-Dichlorofluorescein diacetat;Dichlorofluorescein diacetat;MFCD 37501;Spiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3-one,3',6'-bis(acetyloxy)-2',7'-dichloro-;2',7'-Dichloro-3-oxo-3H-spiro[isobenzofuran-1,9'-xanthene]-3',6'-diyl diacetate;DCDHF DIACETATE;DIACETYLDICHLOROFLUORESCIN | | CAS: | 2044-85-1 | | MF: | C24H14Cl2O7 | | MW: | 485.27 | | EINECS: | | | Product Categories: | Fluorescein and Derivatives;Fluorescent Labels;Fluorescent Probes, Labels, Particles and Stains | | Mol File: | 2044-85-1.mol |  |
| | 2',7'-Dichlorofluorescin diacetate Chemical Properties |
| Melting point | 232-234 °C(lit.) | | Boiling point | 657.9±55.0 °C(Predicted) | | density | 1.59±0.1 g/cm3(Predicted) | | Fp | >109℃ | | storage temp. | 2-8°C | | solubility | DMSO: soluble | | form | Powder or Crystals | | color | Colorless to off-white | | Appearance | Solid Powder | | BRN | 68488 | | InChI | InChI=1S/C24H14Cl2O7/c1-11(27)30-21-9-19-15(7-17(21)25)24(14-6-4-3-5-13(14)23(29)33-24)16-8-18(26)22(31-12(2)28)10-20(16)32-19/h3-10H,1-2H3 | | InChIKey | VQVUBYASAICPFU-UHFFFAOYSA-N | | SMILES | C12(C3=C(C=C(OC(C)=O)C(Cl)=C3)OC3=C1C=C(Cl)C(OC(C)=O)=C3)C1=C(C=CC=C1)C(=O)O2 |
| | 2',7'-Dichlorofluorescin diacetate Usage And Synthesis |
| Description | 2',7'-Dichlorofluorescein diacetate is a cell-permeable fluorogenic probe for detecting reactive oxygen species (ROS) and nitric oxide (NO). | | Chemical Properties | off-white powder or crystals | | Uses | Cell permeable, sensitive indicator of peroxynitrite formation. After hydrolysis of the diacetate groups by cytosolic esterases or base-catalyzed cleavage of the diacetate groups, DCDHF is oxidized by peroxynitrite yielding the highly fluorescent product | | Uses | 2′,7′-Dichlorofluorescein diacetate may be used as a superior gas phase alternative to underivatized fluorescein and as a component/substrate of the 2′,7′-dichlorofluorescein diacetate assay to quantitate reactive oxygen species (ROS). | | Excitation / Emission Maximum | 492 nm/515 nm |
| | 2',7'-Dichlorofluorescin diacetate Preparation Products And Raw materials |
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