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Broussonol E

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Broussonol E Basic information
Product Name:Broussonol E
Synonyms:Broussonol E;4H-1-Benzopyran-4-one, 2-[3,4-dihydroxy-5-(3-methyl-2-buten-1-yl)phenyl]-3,5,7-trihydroxy-6-(3-methyl-2-buten-1-yl)-
CAS:363134-28-5
MF:C25H26O7
MW:438.47
EINECS:
Product Categories:
Mol File:363134-28-5.mol
Broussonol E Structure
Broussonol E Chemical Properties
Melting point 192-193 °C
Boiling point 687.5±55.0 °C(Predicted)
density 1.372±0.06 g/cm3(Predicted)
pka6.83±0.40(Predicted)
Safety Information
MSDS Information
Broussonol E Usage And Synthesis
UsesBroussonol E is a diprenylated flavonol. Broussonol E can be isolated from the leaves of Broussonetia kazinoki. Unlike some dinonylated flavonol derivatives, Broussonol E has no cytotoxicity to human tumor cell lines (A549, HCT-8, KB)[1].
DefinitionChEBI: Papyriflavonol A is a pentahydroxyflavone that is flavone substituted with hydroxy groups at positions 3, 5, 7, 3' and 4' and prenyl groups at positions 6 and 5'. Isolated from Broussonetia papyrifera, it exhibits inhibitory activity against phospholipase A2 and tyrosinase. It has a role as a metabolite, an EC 3.1.1.4 (phospholipase A2) inhibitor and an EC 1.14.18.1 (tyrosinase) inhibitor. It is a member of flavonols, a pentahydroxyflavone and a 3'-hydroxyflavonoid.
References[1] Zhang PC, et al. Five new diprenylated flavonols from the leaves of Broussonetia kazinoki. J Nat Prod. 2001 Sep;64(9):1206-9. DOI:10.1021/np010283o
Broussonol E Preparation Products And Raw materials
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