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| | MVPQJUFFTWWKBT-LBDWYMBGSA-N Basic information |
| Product Name: | MVPQJUFFTWWKBT-LBDWYMBGSA-N | | Synonyms: | MVPQJUFFTWWKBT-LBDWYMBGSA-N;L-Alaninamide, N-[(phenylmethoxy)carbonyl]-L-tyrosyl-L-valyl-N-[(1S)-3-fluoro-1-(2-methoxy-2-oxoethyl)-2-oxopropyl]- (9CI);Caspase 4,Inhibitor,Anti-inflammatory,ZYVADFMK,Caspase 1,Z YVAD FMK,Caspase,inhibit,anti-tumor;Z-YVAD-FMK, Irreversible caspase-1 inhibitor;Z-YVAD-FMK, 10 mM in DMSO | | CAS: | 210344-97-1 | | MF: | C31H39FN4O9 | | MW: | 630.66 | | EINECS: | | | Product Categories: | | | Mol File: | 210344-97-1.mol |  |
| | MVPQJUFFTWWKBT-LBDWYMBGSA-N Chemical Properties |
| Boiling point | 945.2±65.0 °C(Predicted) | | density | 1.261±0.06 g/cm3(Predicted) | | form | Solid | | pka | 9.81±0.15(Predicted) | | color | White to off-white | | Sequence | Z-Tyr-Val-Ala-Asp-FMK |
| | MVPQJUFFTWWKBT-LBDWYMBGSA-N Usage And Synthesis |
| Uses | Z-YVAD-FMK is acell-permeablecaspase-1 and -4 inhibitor withanti-inflammatory and anti-tumor activities[1]. | | IC 50 | Caspase | | References | [1] Li H1,et al.Aluminum hydroxide adjuvants activate caspase-1 and induce IL-1beta and IL-18 release.J Immunol. 2007 Apr 15;178(8):5271-6. DOI:10.4049/jimmunol.178.8.5271
[2] Avivi-Green C, et al. Different molecular events account for butyrate-induced apoptosis in two human colon cancer cell lines.J Nutr. 2002 Jul;132(7):1812-8. DOI:10.1093/jn/132.7.1812 |
| | MVPQJUFFTWWKBT-LBDWYMBGSA-N Preparation Products And Raw materials |
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