2,3-Dcpe hydrochloride manufacturers
- 2,3-DCPE
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- $1980.00
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2026-04-20
- CAS:418788-90-6
- Purity:
- Supply Ability: 10g
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| | 2,3-Dcpe hydrochloride Basic information |
| Product Name: | 2,3-Dcpe hydrochloride | | Synonyms: | 2,3-DCPEHCl;2-[[3-(2,3-DICHLOROPHENOXY)PROPYL]AMINO]ETHANOL HYDROCHLORIDE;2,3-DCPE;Ethanol, 2-[[3-(2,3-dichlorophenoxy)propyl]amino]-;2-[3-(2,3-dichlorophenoxy)propylamino]ethanol;3-DCPE hydrochloride;2,3 DCPE hydrochloride,2,3DCPE hydrochloride;2,3-Dcpe hydrochloride | | CAS: | 418788-90-6 | | MF: | C11H15Cl2NO2 | | MW: | 264.15 | | EINECS: | | | Product Categories: | | | Mol File: | 418788-90-6.mol |  |
| | 2,3-Dcpe hydrochloride Chemical Properties |
| Boiling point | 402.9±40.0 °C(Predicted) | | density | 1.259±0.06 g/cm3(Predicted) | | storage temp. | Desiccate at -20°C | | solubility | 20 mg/ml in DMSO | | pka | 14.78±0.10(Predicted) | | form | Powder | | Water Solubility | Soluble in water at ~25 mg/ml. Also soluble in ethanol, DMSO or DMF at ~20mg/ml. Soluble in PBS, pH 7.2 at ~10 mg/ml. |
| | 2,3-Dcpe hydrochloride Usage And Synthesis |
| Uses | 2,3-DCPE induces apoptosis and downregulates Bcl-XL expression. 2,3-DCPE has anti-tumor activity and can be used in cancer research[1]. | | Biological Activity | Selectively induces apoptosis and downregulates Bcl-XL protein expression in various human cancer cells versus normal cells in vitro . IC 50 values are 0.89 and 12.6 μ M for LoVo human colon cancer cell line and normal human fibroblasts respectively. Induces p21 expression and S-phase arrest in cancer cells via ERK-mediated pathways. | | References | [1] Wu S, et al. Induction of apoptosis and down-regulation of Bcl-XL in cancer cells by a novel small molecule, 2[[3-(2,3-dichlorophenoxy)propyl]amino]ethanol. Cancer Res. 2004 Feb 1;64(3):1110-3. DOI:10.1158/0008-5472.can-03-2790 |
| | 2,3-Dcpe hydrochloride Preparation Products And Raw materials |
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