- Benperidol
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- $118.00
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2026-06-02
- CAS:2062-84-2
- Purity: 99.91%
- Supply Ability: 10g
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| | Benperidol Basic information |
| Product Name: | Benperidol | | Synonyms: | 1-(1-(3-(p-fluorobenzoyl)propyl)-4-piperidyl)-2-benzimidazolinon;1-(1-(3-(p-fluorobenzoyl)propyl)-4-piperidyl)-2-benzimidazolinone;1-(4-Fluorophenyl)-4-[4-(2-hydroxy-1H-benzimidazol-1-yl)-1-piperidinyl]-1-butanone;1-[1-[4-(4-Fluorophenyl)-4-oxobutyl]-4-piperidinyl]-1,3-dihydro-2H-benzimidazol-2-one;1-1-(3-(p-Fluorobenzoyl)propyl)-4-piperidyl-2-benzimidazolinone;2-Benzimidazolinone, 1-[1-[3-(p-fluorobenzoyl)propyl]-4-piperidyl]-;2H-Benzimidazol-2-one, 1-[1-[4-(4-fluorophenyl)-4-oxobutyl]-4-piperidinyl]-1,3-dihydro-;Benperidol | | CAS: | 2062-84-2 | | MF: | C22H24FN3O2 | | MW: | 381.44 | | EINECS: | 218-172-2 | | Product Categories: | | | Mol File: | 2062-84-2.mol |  |
| | Benperidol Chemical Properties |
| Melting point | 170-171.8° | | Boiling point | 230.3°C (rough estimate) | | density | 1.1876 (estimate) | | storage temp. | Store at -20°C | | solubility | Practically insoluble in water, freely soluble in dimethylformamide, soluble in methylene chloride, slightly soluble in ethanol (96 per cent). | | pka | 12.04±0.30(Predicted) | | form | Solid | | color | White to off-white | | Major Application | pharmaceutical (small molecule) | | InChI | 1S/C22H24FN3O2/c23-17-9-7-16(8-10-17)21(27)6-3-13-25-14-11-18(12-15-25)26-20-5-2-1-4-19(20)24-22(26)28/h1-2,4-5,7-10,18H,3,6,11-15H2,(H,24,28) | | InChIKey | FEBOTPHFXYHVPL-UHFFFAOYSA-N | | SMILES | Fc1ccc(cc1)C(=O)CCCN2CCC(CC2)[n]3c4c([nH][c]3=O)cccc4 | | CAS DataBase Reference | 2062-84-2(CAS DataBase Reference) | | NIST Chemistry Reference | Benperidol(2062-84-2) |
| | Benperidol Usage And Synthesis |
| Chemical Properties | White or almost white powder. | | Originator | Frenactil,Clin-Comar-Byla,France,1965 | | Uses | Antipsychotic. | | Definition | ChEBI: 3-[1-[4-(4-fluorophenyl)-4-oxobutyl]-4-piperidinyl]-1H-benzimidazol-2-one is an aromatic ketone. | | Manufacturing Process | A mixture of 3.4 parts of γ-chloro-4-fluorobutyrophenone, 4 parts of 1-(4-
piperidyl)-2-benzimidazolinone hydrochloride, 6 parts of sodium carbonate and
0.1 part of potassium iodide in 176 parts of 4-methyl-2-pentanone is stirred
and refluxed for 48 hours. The reaction mixture is cooled and 120 parts of
water is added. The separated organic layer is dried over magnesium sulfate
and the solvent is evaporated to leave an oily residue which is dissolved in
dilute hydrochloric acid and boiled. The acidic solution is filtered and cooled at
room temperature whereupon there crystallizes from solution 1-(1-[γ-(4-
fluorobenzoyl)propyl] -4-piperidyl)-2-benzimidazolinone hydrochloride hydrate
melting at about 134°-142°C. | | Therapeutic Function | Tranquilizer |
| | Benperidol Preparation Products And Raw materials |
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