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| | 10-POHSA Basic information |
| Product Name: | 10-POHSA | | Synonyms: | 10-POHSA | | CAS: | | | MF: | C34H64O4 | | MW: | 536.86956 | | EINECS: | | | Product Categories: | | | Mol File: | Mol File |  |
| | 10-POHSA Chemical Properties |
| solubility | DMF: 20 mg/ml
DMSO: 15 mg/ml
Ethanol: 20 mg/ml
Ethanol: PBS(pH 7.2) (1:1): 0.5 mg/ml |
| | 10-POHSA Usage And Synthesis |
| Description | 10-POHSA is a newly identified endogenous lipid that belongs to a collection of branched fatty acid esters of hydroxy fatty acids (FAHFAs). It is a FAHFA in which palmitoleic acid (Item No. 10009871) is esterified to 10-hydroxy stearic acid. Among the FAHFA family members, PAHSAs are the most abundant in the adipose tissue of glucose tolerant AG4OX mice, which overexpress the Glut4 glucose transporter specifically in adipose tissue.1 As other FAHFAs improve glucose tolerance, stimulate insulin secretion, and have anti-inflammatory effects, 10-POHSA may be a bioactive lipid with roles in metabolic syndrome and inflammation.1WARNING This product is not for human or veterinary use. | | References | [1] MARK M YORE. Discovery of a class of endogenous mammalian lipids with anti-diabetic and anti-inflammatory effects.[J]. Cell, 2014, 159 2: 318-332. DOI: 10.1016/j.cell.2014.09.035
[2] PRATIK ARYAL. Distinct biological activities of isomers from several families of branched fatty acid esters of hydroxy fatty acids (FAHFAs).[J]. Journal of Lipid Research, 2021: 100108. DOI: 10.1016/j.jlr.2021.100108 |
| | 10-POHSA Preparation Products And Raw materials |
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