| Company Name: |
Shanghai Raise Chemical Technology Co.,Ltd
|
| Tel: |
15026594951 |
| Email: |
rs@raise-chem.com |
| Products Intro: |
Product Name:5-(5-acetyl-6-methyl-2-oxo-1-(3-(trifluoromethyl)phenyl)-1,2,3,4tetrahydropyrimidin-4-yl)picolinonitrile
CAS:675103-35-2
Purity:97% HPLC Package:1g;5g
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| Company Name: |
Hefei Mokai Pharmaceutical Technology Co., Ltd
|
| Tel: |
18130062233 |
| Email: |
690231469@qq.com |
| Products Intro: |
Product Name:5-(5-Acetyl-6-methyl-2-oxo-1-(3-(trifluoromethyl)phenyl)-1,2,3,4-tetrahydropyrimidin-4-yl)picolinonitrile
CAS:675103-35-2
Purity:97% Package:5g25g100g
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5-(5-acetyl-6-methyl-2-oxo-1-(3-(trifluoromethyl)phenyl)-1,2,3,4tetrahydropyrimidin-4-yl)picolinonitrile manufacturers
- BAY-678 racemate
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- $1980.00
-
2026-04-20
- CAS:675103-35-2
- Purity:
- Supply Ability: 10g
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| | 5-(5-acetyl-6-methyl-2-oxo-1-(3-(trifluoromethyl)phenyl)-1,2,3,4tetrahydropyrimidin-4-yl)picolinonitrile Basic information |
| Product Name: | 5-(5-acetyl-6-methyl-2-oxo-1-(3-(trifluoromethyl)phenyl)-1,2,3,4tetrahydropyrimidin-4-yl)picolinonitrile | | Synonyms: | 5-(5-acetyl-6-methyl-2-oxo-1-(3-(trifluoromethyl)phenyl)-1,2,3,4tetrahydropyrimidin-4-yl)picolinonitrile;2-Pyridinecarbonitrile, 5-[5-acetyl-1,2,3,4-tetrahydro-6-methyl-2-oxo-1-[3-(trifluoromethyl)phenyl]-4-pyrimidinyl]-;BAY 678 racemate,BAY678 racemate;BAY-678 racemate | | CAS: | 675103-35-2 | | MF: | C20H15F3N4O2 | | MW: | 400.35 | | EINECS: | | | Product Categories: | | | Mol File: | 675103-35-2.mol |  |
| | 5-(5-acetyl-6-methyl-2-oxo-1-(3-(trifluoromethyl)phenyl)-1,2,3,4tetrahydropyrimidin-4-yl)picolinonitrile Chemical Properties |
| Boiling point | 623.9±55.0 °C(Predicted) | | density | 1.42±0.1 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | DMSO: ≥ 150 mg/mL (374.67 mM); Water: < 0.1 mg/mL (insoluble) | | pka | 9.35±0.70(Predicted) | | form | Solid | | color | Light yellow to yellow |
| | 5-(5-acetyl-6-methyl-2-oxo-1-(3-(trifluoromethyl)phenyl)-1,2,3,4tetrahydropyrimidin-4-yl)picolinonitrile Usage And Synthesis |
| Uses | BAY-678 racemate is a racemate of BAY-678. BAY-678 is an orally bioavailable, highly potent, selective and cell-permeable inhibitor of human neutrophil elastase (HNE), with an IC50 of 20 nM. BAY-678 is also nominated as a chemical probe to the public via the Structural Genomics Consortium (SGC). | | References | [1] von Nussbaum F, et al. Freezing the Bioactive Conformation to Boost Potency: The Identification of BAY 85-8501, a Selective and Potent Inhibitor of Human Neutrophil Elastase for Pulmonary Diseases. ChemMedChem. 2015 Jul;10(7):1163-73. DOI:10.1002/cmdc.201500131 |
| | 5-(5-acetyl-6-methyl-2-oxo-1-(3-(trifluoromethyl)phenyl)-1,2,3,4tetrahydropyrimidin-4-yl)picolinonitrile Preparation Products And Raw materials |
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