ANGELIC ANHYDRIDE

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ANGELIC ANHYDRIDE manufacturers

  • Angelic anhydride
  • Angelic anhydride pictures
  • 2023-02-24
  • CAS:94487-74-8
  • Min. Order: 20mg
  • Purity: ≥98%(HPLC)
  • Supply Ability: 100 g
ANGELIC ANHYDRIDE Basic information
Product Name:ANGELIC ANHYDRIDE
Synonyms:Angelic anhydride 94487-74-8;ANGELIC ANHYDRIDE;CIS-2-METHYLCROTONIC ANHYDRIDE;CIS-2,3-DIMETHYLACRYLIC ANHYDRIDE;2-METHYLISOCROTONIC ANHYDRIDE;(Z)-2-METHYL-2-BUTENOIC ANHYDRIDE;Bis[(Z)-2-methyl-2-butenoic acid] anhydride;Bis[(Z)-2-methyl-2-butenoic] anhydride
CAS:94487-74-8
MF:C10H14O3
MW:182.22
EINECS:
Product Categories:
Mol File:94487-74-8.mol
ANGELIC ANHYDRIDE Structure
ANGELIC ANHYDRIDE Chemical Properties
Boiling point 108 °C / 13mmHg
density 1,02 g/cm3
refractive index 1.4720-1.4750
storage temp. 0-10°C
solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form clear liquid
color Colorless to Light orange to Yellow
InChIKeyLIHLSLRANKCHLV-SFECMWDFSA-N
Safety Information
RIDADR 3265
HS Code 2916.19.5000
HazardClass 8
PackingGroup III
MSDS Information
ANGELIC ANHYDRIDE Usage And Synthesis
UsesAngelic Anhydride is a reagent in the improved synthesis of angelate esters, which are the active chemical behind the strong pain-relieving and spasmolytic action of extracts from the plant butterbur.
SynthesisAngelic anhydride (dahuric anhydride) was prepared as follows: to a solution of angelic acid (5 g, 50 mmol) in dichloromethane (100 mL) at room temperature was added N,N’ Dicyclohexylcarbodiimide (8.6 mL, 60% in xylene, 25 mmol). The reaction mixture was stirred at this temperature for 1 hour. The precipitate was filtered. The filtrate was concentrated in vacuum. The residue was purified by chromatography (petroleum ether/ethyl acetate 10:1) to give 4.3 g of the title compound dahuric anhydride as an oil (94%). 1H NMR (300 MHz, CDCl3)δ 6.376.25 (m, 2H), 2.06 (dq, J=7.4, 1.5 Hz, 6H), 1.971.93 (m, 6H).
ANGELIC ANHYDRIDE Preparation Products And Raw materials
Tag:ANGELIC ANHYDRIDE(94487-74-8) Related Product Information
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