LCL521 manufacturers
- LCL521
-
- $1360.00
-
2026-07-27
- CAS:1226851-11-1
- Purity:
- Supply Ability: 10g
- LCL521
-
- $1360.00
-
2026-07-27
- CAS:1226851-11-1
- Purity:
- Supply Ability: 10g
- LCL521
-
- $1360.00
-
2025-07-27
- CAS:1226851-11-1
- Purity:
- Supply Ability: 10g
|
| Product Name: | LCL521 | | Synonyms: | LCL521;Glycine, N,N-dimethyl-, 1,1'-[(1R,2R)-1-(4-nitrophenyl)-2-[(1-oxotetradecyl)amino]-1,3-propanediyl] ester;LCL521,LCL-521;(1R,2R)-1-(4-Nitrophenyl)-2-tetradecanamidopropane-1,3-diyl bis(2-(dimethylamino)acetate) | | CAS: | 1226851-11-1 | | MF: | C31H52N4O7 | | MW: | 592.77 | | EINECS: | | | Product Categories: | | | Mol File: | 1226851-11-1.mol |  |
| | LCL521 Chemical Properties |
| Boiling point | 697.4±55.0 °C(Predicted) | | density | 1.093±0.06 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | DMSO:150.0(Max Conc. mg/mL);253.05(Max Conc. mM)
Ethanol:100.0(Max Conc. mg/mL);168.7(Max Conc. mM) | | form | Oil | | pka | 14.18±0.46(Predicted) | | color | Colorless to light yellow |
| | LCL521 Usage And Synthesis |
| Uses | LCL521 is an acid ceramidase (ACDase) inhibitor. LCL521 also inhibits the lysosomal acid sphingomyelinase (ASMase)[1]. | | References | [1] Bai A, et al. Targeting (cellular) lysosomal acid ceramidase by B13: design, synthesis and evaluation of novel DMG-B13 ester prodrugs. Bioorg Med Chem. 2014 Dec 15;22(24):6933-44. DOI:10.1016/j.bmc.2014.10.025 |
| | LCL521 Preparation Products And Raw materials |
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