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J & K SCIENTIFIC LTD.
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18210857532; 18210857532 |
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jkinfo@jkchemical.com |
| Products Intro: |
Product Name:IMidaprilat
CAS:89371-44-8
Package:10Mg,1Mg
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IMIDAPRILAT manufacturers
- Imidaprilat
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- $0.00 / 10mg
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2025-09-03
- CAS:89371-44-8
- Min. Order: 10mg
- Purity: 98%
- Supply Ability: 500mg
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| | IMIDAPRILAT Basic information |
| Product Name: | IMIDAPRILAT | | Synonyms: | (4S)-3-[(2S)-2-[[(1S)-1-carboxy-3-phenylpropyl]amino]propanoyl]-1-methyl-2-oxoimidazolidine-4-carboxylic acid;IMIDAPRILAT;(4S)-3-{(2S)-2-[N-((1S)-1-Carboxy-3-phenylpropyl)amino]propionyl}-1-methyl-2-oxoimidazolidine-4-carboxylic Acid;Imidapril Diacid;(4S)-3-[(2S)-N-[(1S)-1-Carboxy-3-phenylpropyl]alanyl]-1-methyl-2-oxo-4-imidazolidinecarboxylic acid;6366A;Imidaprilate;4-Imidazolidinecarboxylic acid, 3-[(2S)-2-[[(1S)-1-carboxy-3-phenylpropyl]amino]-1-oxopropyl]-1-methyl-2-oxo-, (4S)- | | CAS: | 89371-44-8 | | MF: | C18H23N3O6 | | MW: | 377.39 | | EINECS: | | | Product Categories: | Intermediates & Fine Chemicals;Pharmaceuticals | | Mol File: | 89371-44-8.mol |  |
| | IMIDAPRILAT Chemical Properties |
| Melting point | 180-1820C | | alpha | D19 -88.4° (c = 1 in 5% NaHCO3) | | Boiling point | 592.1±60.0 °C(Predicted) | | density | 1.356±0.06 g/cm3(Predicted) | | storage temp. | -20°C Freezer | | solubility | Aqueous Acid (Slightly, Heated, Sonicated), DMSO (Slightly, Heated) | | form | Solid | | pka | 2.17±0.10(Predicted) | | color | White to Off-White |
| | IMIDAPRILAT Usage And Synthesis |
| Chemical Properties | White to Off-White Solid | | Uses | Antihypertensive. | | Definition | ChEBI: Imidaprilat is a member of the class of imidazolidines that is imidapril in which the ethyl ester group has been hydrolysed to the corresponding acid group. It is the active metabolite of imidapril used to treat hypertension. It has a role as an EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor, an antihypertensive agent and a drug metabolite. It is a dipeptide, a member of imidazolidines, a secondary amino compound, a dicarboxylic acid and a N-acylurea. It is functionally related to an imidapril. | | in vivo | Imidaprilate (≥0.2 mg/kg) inhibits angiotensin I (AT-I)-induced pressor response. TA-6366 lowers the blood pressure in two-kidney one-clip renal hypertensive rats at 0.5-2 mg/kg via oral administration, and in spontaneously hypertensive rats (SHRs) at 2 to 10 mg/kg[1]. |
| | IMIDAPRILAT Preparation Products And Raw materials |
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