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| Product Name: | S15535 | | Synonyms: | Piperazine,1-(2,3-dihydro-1,4-benzodioxin-5-yl)-4-(2,3-dihydro-1H-inden-2-yl)-;1-(2,3-Dihydro-1,4-benzodioxin-5-yl)-4-(2,3-dihydro-1H-inden-2-yl)piperazin;4-(benzodioxan-5-yl)-1-(indan-2-yl)piperazine;S15535 >=98% (HPLC), solid | | CAS: | 146998-34-7 | | MF: | C21H24N2O2 | | MW: | 336.43 | | EINECS: | | | Product Categories: | | | Mol File: | 146998-34-7.mol |  |
| | S15535 Chemical Properties |
| Boiling point | 504.5±50.0 °C(Predicted) | | density | 1.228±0.06 g/cm3(Predicted) | | storage temp. | 2-8°C | | solubility | DMSO: ~6 mg/mL | | form | solid | | pka | 7.84±0.70(Predicted) | | color | white | | InChI | 1S/C21H24N2O2/c1-2-5-17-15-18(14-16(17)4-1)22-8-10-23(11-9-22)19-6-3-7-20-21(19)25-13-12-24-20/h1-7,18H,8-15H2 | | InChIKey | QJPPEMXOOWNICQ-UHFFFAOYSA-N | | SMILES | C1COc2c(O1)cccc2N3CCN(CC3)C4Cc5ccccc5C4 |
| Hazard Codes | N | | Risk Statements | 50 | | Safety Statements | 61 | | RIDADR | UN 3077 9/PG 3 | | WGK Germany | 3 | | Storage Class | 11 - Combustible Solids | | Hazard Classifications | Aquatic Acute 1
Aquatic Chronic 1 |
| | S15535 Usage And Synthesis |
| Uses | S15535 has been used as a serotonin 1A receptor (5-HT1A) agonist in zebrafish.', 'S15535 may be used in histamine 5-HT1A-medaited cell signaling studies. | | Biological Activity | S15535, a benzodioxane, is a selective but partial agonist of histamine serotonin 1A (5-HT1A) receptor. It activates presynaptic 5-HT1A receptors and suppresses the release of hippocampal 5-HT. It acts as an anxiolytic agent and modulates the cholinergic and cognitive function in rodents.', 'Potent, orally active, partial 5-HT1A receptor agonist |
| | S15535 Preparation Products And Raw materials |
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