Furo[3,4-b]pyridin-5(7H)-one, 4-[3-(4-fluorophenyl)-1-methyl-1H-pyrazol-4-yl]-

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Furo[3,4-b]pyridin-5(7H)-one, 4-[3-(4-fluorophenyl)-1-methyl-1H-pyrazol-4-yl]- Suppliers list
Company Name: Shanghai Haozhixiang Biotechnology Co., Ltd  Gold
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Furo[3,4-b]pyridin-5(7H)-one, 4-[3-(4-fluorophenyl)-1-methyl-1H-pyrazol-4-yl]- manufacturers

  • CK1-IN-2
  • CK1-IN-2 pictures
  • $68.00
  • 2026-07-27
  • CAS:1383376-92-8
  • Purity: 99.31%
  • Supply Ability: 10g
Furo[3,4-b]pyridin-5(7H)-one, 4-[3-(4-fluorophenyl)-1-methyl-1H-pyrazol-4-yl]- Basic information
Product Name:Furo[3,4-b]pyridin-5(7H)-one, 4-[3-(4-fluorophenyl)-1-methyl-1H-pyrazol-4-yl]-
Synonyms:Furo[3,4-b]pyridin-5(7H)-one, 4-[3-(4-fluorophenyl)-1-methyl-1H-pyrazol-4-yl]-;PF-05251749（CK1-IN-2）;CK1-IN-2;4-[3-(4-Fluorophenyl)-1-methyl-1H-pyrazol-4-yl]furo[3,4-b]pyridin-5(7H)-one
CAS:1383376-92-8
MF:C17H12FN3O2
MW:309.29
EINECS:
Product Categories:
Mol File:1383376-92-8.mol
Furo[3,4-b]pyridin-5(7H)-one, 4-[3-(4-fluorophenyl)-1-methyl-1H-pyrazol-4-yl]- Structure
Furo[3,4-b]pyridin-5(7H)-one, 4-[3-(4-fluorophenyl)-1-methyl-1H-pyrazol-4-yl]- Chemical Properties
Boiling point 509.7±50.0 °C(Predicted)
density 1.41±0.1 g/cm3(Predicted)
pka0.89±0.20(Predicted)
form Solid
color Off-white to light yellow
InChIInChI=1S/C17H12FN3O2/c1-21-8-13(16(20-21)10-2-4-11(18)5-3-10)12-6-7-19-14-9-23-17(22)15(12)14/h2-8H,9H2,1H3
InChIKeyXISSYJGQGSMWHO-UHFFFAOYSA-N
SMILESC12COC(=O)C1=C(C1=CN(C)N=C1C1=CC=C(F)C=C1)C=CN=2
Safety Information
MSDS Information
Furo[3,4-b]pyridin-5(7H)-one, 4-[3-(4-fluorophenyl)-1-methyl-1H-pyrazol-4-yl]- Usage And Synthesis
UsesCK1-IN-2 (compound Nr.4) is a potent CK1 inhibitor with an IC50 values of 123, 19.8, 26.8, 74.3 nM for CK1a, CK1d, CK1e, p38a, respectively[1].
IC 50CKIα: 123 nM (IC50)
References[1] Joris De Maeyer, et al. Casein kinase 1 inhibitors for use in the treatment of diseases related to dux4 expression such as muscular dystrophy and cancer. WO2020249717A1.
Furo[3,4-b]pyridin-5(7H)-one, 4-[3-(4-fluorophenyl)-1-methyl-1H-pyrazol-4-yl]- Preparation Products And Raw materials
Tag:Furo[3,4-b]pyridin-5(7H)-one, 4-[3-(4-fluorophenyl)-1-methyl-1H-pyrazol-4-yl]-(1383376-92-8) Related Product Information
1H-Pyrazole-4-carboxylic acid, 1-methyl-3-(3-pyridinyl)-, methyl ester Furo[3,4-b]pyridin-5(7H)-one, 4-[3-(4-fluorophenyl)-1-methyl-1H-pyrazol-4-yl]- 1H-Pyrazole-4-carboxylic acid, 1-methyl-3-(4-pyridinyl)-, methyl ester CK1-IN-2 hydrochloride SR 3029 Anti-Aging Compound Library