VH032 thiol manufacturers
- VH032 thiol
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- $1980.00
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2025-12-22
- CAS:2098836-54-3
- Purity:
- Supply Ability: 10g
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| | VH032 thiol Basic information |
| Product Name: | VH032 thiol | | Synonyms: | VH032 THIOL (VHL LIGAND 6);VHL ligand 6;L-Prolinamide, N-acetyl-3-mercapto-L-valyl-4-hydroxy-N-[[4-(4-methyl-5-thiazolyl)phenyl]methyl]-, (4R)-;(2S,4R)-1-((R)-2-Acetamido-3-mercapto-3-methylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide;(2S,4R)-1-[(2R)-2-acetamido-3-methyl-3-sulfanylbutanoyl]-4-hydroxy-N-{[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl}pyrrolidine-2-carboxamide | | CAS: | 2098836-54-3 | | MF: | C23H30N4O4S2 | | MW: | 490.64 | | EINECS: | | | Product Categories: | | | Mol File: | 2098836-54-3.mol |  |
| | VH032 thiol Chemical Properties |
| Boiling point | 805.1±65.0 °C(Predicted) | | density | 1.304±0.06 g/cm3(Predicted) | | solubility | DMSO : 50 mg/mL (101.91 mM; Need ultrasonic) | | pka | 10.17±0.10(Predicted) | | form | Solid | | color | White to light yellow |
| | VH032 thiol Usage And Synthesis |
| Uses | VH032 thiol (VHL ligand 6) is a VHL ligand, which binds to pan-BET inhibitor JQ1 via a linker to form PROTAC[1]. | | IC 50 | VHL | | storage | Store at -20°C | | References | [1] Gadd MS, et al. Structural basis of PROTAC cooperative recognition for selective protein degradation. Nat Chem Biol. 2017 May;13(5):514-521. DOI:10.1038/nchembio.2329 |
| | VH032 thiol Preparation Products And Raw materials |
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