|
|
| | α-Linolenic acid ethyl ester-d5 Basic information |
| Product Name: | α-Linolenic acid ethyl ester-d5 | | Synonyms: | α-Linolenic Acid ethyl ester-d5;9Z,12Z,15Z-octadecatrienoic-17,17,18,18,18-d5 acid, ethyl ester;A-Linolenic acid ethyl ester-D5;Linolenic acid (18:3), ethyl ester (17,17,18,18,18-D?, 98%) CP 95% | | CAS: | 203633-16-3 | | MF: | C20H34O2 | | MW: | 306.49 | | EINECS: | | | Product Categories: | | | Mol File: | 203633-16-3.mol |  |
| | α-Linolenic acid ethyl ester-d5 Chemical Properties |
| storage temp. | Store at -20°C | | solubility | Ethanol: soluble |
| | α-Linolenic acid ethyl ester-d5 Usage And Synthesis |
| Description | α-Linolenic acid ethyl ester-d5 is intended for use as an internal standard for the quantification of α-linolenic acid ethyl ester by GC- or LC-MS. α-Linolenic acid ethyl ester is an esterified form of α-linolenic acid . It increases cyclin E levels and the activity of Cdk2/cyclin E, ERK, and JNK in hepatic stellate cells when used at a concentration of 50 μM.1 α-Linolenic acid ethyl ester (25 μg/ml) inhibits the growth of S. mutans, C. albicans, and P. gingivalis by 98, 72, and 92%, respectively, in vitro.2 It has been found in biodiesel produced from castor oil using ethanol.3 α-Linolenic acid ethyl ester has been used as a substrate in lipid peroxidation assays for antioxidant activity.4 | | Uses | Ethyl linolenate-d5 is the deuterium labeled Ethyl linolenate. Ethyl linolenate is a fatty acid ethyl ester (FAEE). Ethyl linolenate plays an active role in inhibition of the cellular production on melanin with an IC50 of 70 μM. Anti-melanogenesis Effects[1]. | | References | 1. Li, J., Hu, W., Baldassare, J.J., et al. The ethanol metabolite, linolenic acid ethyl ester, stimulates mitogen-activated protein kinase and cyclin signaling in hepatic stellate cells Life Sci. 73(9),1083-1096(2003).
2. Huang, C.B., and Ebersole, J.L. A novel bioactivity of omega-3 polyunsaturated fatty acids and their ester derivatives Mol. Oral Microbiol. 25(1),75-80(2010).
3. Conceio, M.M., Fernandes, V.J., Jr., Bezerra, A.F., et al. Dynamic kinetic calculation of castor oil biodiesel J. Therm. Anal. Calorim. 87(3),865-869(2007).
4. Miyake, T., and Shibamoto, T. Antioxidative activities of natural compounds found in plants J. Agric. Food Chem. 45(5),1819-1822(1997). |
| | α-Linolenic acid ethyl ester-d5 Preparation Products And Raw materials |
|