| Company Name: |
BOC Sciences |
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16314854226; +8616314854226 |
| Email: |
inquiry@bocsci.com |
|
| | FD 12-9 Basic information |
| Product Name: | FD 12-9 | | Synonyms: | FD 12-9;Ac12Az9;Benzoic acid, 3-[[[4-oxo-2-[4-[2-[2-[2-[4-[4-[(4-oxo-2-phenyl-4H-1-benzopyran-7-yl)oxy]butyl]-1H-1,2,3-triazol-1-yl]ethoxy]ethoxy]ethoxy]phenyl]-4H-1-benzopyran-3-yl]oxy]methyl]-, methyl ester | | CAS: | 1451741-22-2 | | MF: | C51H47N3O11 | | MW: | 877.93 | | EINECS: | | | Product Categories: | | | Mol File: | 1451741-22-2.mol |  |
| | FD 12-9 Chemical Properties |
| Boiling point | 1007.8±75.0 °C(Predicted) | | density | 1.28±0.1 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | Soluble in DMSO | | pka | 1.42±0.10(Predicted) |
| | FD 12-9 Usage And Synthesis |
| Uses | FD 12-9 is a flavonoid dimer, acts as a dual inhibitor of P-gp and BCRP, with EC50s of 285 nM and 0.9 nM, respectively. Anti-glioblastoma activity[1]. | | References | [1] Hu Xuesen, et al. Developing a novel strategy to treat glioblastoma : improving brain bioavailability of sorafenib with a synthetic flavonoid dimer to inhibit drug efflux in blood brain barrier. |
| | FD 12-9 Preparation Products And Raw materials |
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