ALK2-IN-2 manufacturers
- ALK2-IN-2
-
- $39.00
-
2026-07-27
- CAS:2254409-25-9
- Purity: 99.86%
- Supply Ability: 10g
- ALK2-IN-2
-
- $39.00
-
2026-07-27
- CAS:2254409-25-9
- Purity: 99.86%
- Supply Ability: 10g
- ALK2-IN-2
-
- $56.00
-
2025-07-21
- CAS:2254409-25-9
- Purity: 99.55%
- Supply Ability: 10g
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| | ALK2-IN-2 Basic information |
| Product Name: | ALK2-IN-2 | | Synonyms: | ALK2-IN-2;ALK2 inhibitor 2;ALK2 IN 2,ALK2IN2,ALK-2-IN-2;1-Naphthalenesulfonamide, 4-[6-[4-[1-(1-pyrrolidinyl)ethyl]phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]-;ALK2-IN-2, 10 mM in DMSO | | CAS: | 2254409-25-9 | | MF: | C28H27N5O2S | | MW: | 497.61 | | EINECS: | | | Product Categories: | | | Mol File: | 2254409-25-9.mol |  |
| | ALK2-IN-2 Chemical Properties |
| density | 1.38±0.1 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | DMSO : 125 mg/mL (251.20 mM; Need ultrasonic) | | form | Solid | | pka | 9.82±0.30(Predicted) | | color | Light yellow to yellow |
| | ALK2-IN-2 Usage And Synthesis |
| Uses | ALK2-IN-2 is a potent and selective inhibitor of activin receptor-like kinase 2 (ALK2) with an IC50 of 9 nM, and over 700-fold selectivity against ALK3[1]. | | IC 50 | ACVR1: 9 nM (IC50) | | References | [1] Jiang JK, et al. Discovery of 3-(4-sulfamoylnaphthyl)pyrazolo[1,5-a]pyrimidines as potent and selective ALK2 inhibitors. Bioorg Med Chem Lett. 2018 Nov 1;28(20):3356-3362. DOI:10.1016/j.bmcl.2018.09.006 |
| | ALK2-IN-2 Preparation Products And Raw materials |
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