| Company Name: |
TargetMol Chemicals Inc.
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| Tel: |
15002134094 |
| Email: |
marketing@targetmol.cn |
| Products Intro: |
Product Name:PrPSc-IN-1
CAS:1315475-30-9
Package:25mg/RMB 10600
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| | 4-Quinolinecarboxaldehyde, 2-(7-methoxypyrrolo[1,2-a]quinoxalin-4-yl)hydrazone Basic information |
| | 4-Quinolinecarboxaldehyde, 2-(7-methoxypyrrolo[1,2-a]quinoxalin-4-yl)hydrazone Chemical Properties |
| storage temp. | Store at -20°C | | solubility | Soluble in DMSO |
| | 4-Quinolinecarboxaldehyde, 2-(7-methoxypyrrolo[1,2-a]quinoxalin-4-yl)hydrazone Usage And Synthesis |
| Description | PrPSc-IN-1 is a fluorescent probe, binds to the misfolded protein PrPSc, inhibits its accumulation, with an IC50 of 1.6 μM. Anti-prion activity[1].
IC50:1.6 μM (PrPSc)[1] | | Uses | PrPSc-IN-1 is a fluorescent probe, binds to the misfolded protein PrPSc, inhibits its accumulation, with an IC50 of 1.6 μM. Anti-prion activity[1]. | | References | [1]. Zaccagnini L, et al. Identification of novel fluorescent probes preventing PrPSc replication in prion diseases. Eur J Med Chem. 2017 Feb 15;127:859-873. |
| | 4-Quinolinecarboxaldehyde, 2-(7-methoxypyrrolo[1,2-a]quinoxalin-4-yl)hydrazone Preparation Products And Raw materials |
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